谢晶日教授经验方治疗脾胃湿热型反流性食管炎的临床观察  

Clinical Observation of Empirical Prescription in Treating RE of Damp-Heat of Spleen and Stomach by Professor XIE Jingri

作　　者：蔡宏波[1] 王海强[1] 蔡宏宇 李昊霖 梁国英[1] CAI Hongbo;WANG Haiqiang;CAI Hongyu;LI Haolin;LIANG Guoying(The First Affiliated Hospital of Heilongjiang University of Chinese Medicine,Harbin 150040,China;Harbin Hospital of Traditional Chinese Medicine,Harbin 150070,China;Changchun Sci-Tech University,Changchun 130600,China)

机构地区：[1]黑龙江中医药大学附属第一医院,黑龙江哈尔滨150040 [2]哈尔滨市中医医院,黑龙江哈尔滨150070 [3]长春科技学院,吉林长春130600

出　　处：《中医药学报》2022年第2期64-67,共4页Acta Chinese Medicine and Pharmacology

基　　金：2016年全国名老中医药专家传承工作室建设项目(国中医药人教发[2016]42号);第六批全国老中医药专家学术经验继承工作项目(国中医药人教发[2017]29号);黑龙江省博士后科研启动项目(LBH-Q17169);全国中医临床特色技术传承骨干人才培训项目(国中医药人教函[2019]36号)。

摘　　要：目的:观察谢晶日教授经验方治疗脾胃湿热型反流性食管炎的临床疗效。方法:选取黑龙江中医药大学附属第一医院门诊及住院的脾胃湿热型反流性食管炎患者72例,随机分为对照组及治疗组各36例。两组均采用抑酸、促胃肠动力及黏膜保护等对症治疗;在此基础上,治疗组加服谢晶日教授经验方,连续治疗4周;观察治疗后各组患者的临床总有效率、临床症状评分、生存质量评分及不良反应发生率。结果:治疗组临床总有效率为91.67%(33/36),显著优于对照组的72.22%(26/36),差异有统计学意义(P<0.05);两组患者治疗后,均可有效降低其临床症状评分,同时有效提升生存质量评分,尤其在精神状态、躯体功能、生理功能评分的改善显著优于单独应用西医对症治疗组(P<0.05),且不良反应发生率(11.11%,4/36)亦低于对照组(19.44%,7/36)。结论:谢晶日教授经验方可显著提升脾胃湿热型反流性食管炎患者的临床总有效率,并降低临床症状评分,提高生存质量,安全有效。Objective:To observe the clinical effect of professor XIE Jingri’s empirical prescription in the treatment of reflux esophagitis(RE)of damp-heat of Spleen and Stomach.Methods:72 RE patients with Spleen and Stomach damp-heat were randomly divided into the control group and the treatment group,with 36 cases in each group.The control group was treated with acid suppression,gastrointestinal motility promotion and mucosal protection;on this basis,the treatment group was also treated with empirical prescription for 4 weeks by professor XIE Jingri.The clinical total effective rate,clinical symptom score,quality of life score and incidence of adverse reactions were observed after the treatment in the two groups.Results:The total effective rate of the treatment group was 91.67%(33/36),which was significantly higher than 72.22%(26/36)of the control group(P<0.05).After the treatment,both groups could effectively reduce the clinical symptom score and improve quality of life score,and the treatment group was superior to the control group in terms of improving mental state,physical function and physiological function score(P<0.05).The incidence of adverse reactions was 11.11%(4/36)in the treatment group,which was lower than 19.44%(7/36)in the control group.Conclusion:Professor XIE Jingri’s empirical prescription can significantly improve the clinical total effective rate in treating RE of Spleen and Stomach damp-heat,it can reduce the clinical symptom score and improve the quality of life.The therapy is safe and effective.

关 键 词：谢晶日教授经验方 脾胃湿热 反流性食管炎 临床观察 

分 类 号：R256.3[医药卫生—中医内科学]