流行性腮腺炎性睾丸炎的致病机制及诊治现状  

Research progress of pathogenesis, diagnosis and treatment of epidemic mumps orchitis

作　　者：刘鑫[1,2] 张哲[1,2] 赵连明[1,2] 姜辉[1,2] LIU Xin;ZHANG Zhe;ZHAO Lianming;JIANG Hui(Department of Urology,Peking University Third Hospi-tal,Beijing 100191,China;Reproductive Medicine Center,Peking University Third Hospital,Beijing 100191,China)

机构地区：[1]北京大学第三医院泌尿外科,北京100191 [2]北京大学第三医院生殖医学中心,北京100191

出　　处：《中国性科学》2022年第1期1-4,共4页Chinese Journal of Human Sexuality

摘　　要：流行性腮腺炎性睾丸炎(EMO)是青春期及成年男性流行性腮腺炎最常见的一类并发症,可引起急性期睾丸疼痛肿大、远期睾丸萎缩、生精功能障碍,并极易导致男性不育。约30%青春期后患流行性腮腺炎的男性会诱发睾丸炎,导致不孕或生育力低下。在我国,青春期后男性EMO所导致的不育患者数量非常之多,本文就EMO的病因及流行病学、发病机制、临床表现、诊治现状作一综述,并重点关注生育能力低下的EMO患者的致病机制及诊治现状。研究EMO的致病机制不仅有助于EMO患者的诊治,也将为预防流行性腮腺炎患者并发睾丸炎提供一种新思路。Epidemic mumps orchitis(EMO) is the most common complication of mumps in adolescent and adult males, which can cause acute testicular pain and enlargement, long-term testicular atrophy, spermatogenic dysfunction, and easily lead to male infertility. About 30% of men who develop mumps after puberty develop orchitis that leads to infertility or low fertility. In China, the number of male infertility patients caused by EMO after puberty is very large. This article reviews the etiology, epidemiology, pathogenesis, clinical manifestations, diagnosis and treatment of EMO, and focuses on the pathogenesis, diagnosis and treatment of EMO with low fertility. The study of the pathogenesis of EMO not only contributes to the diagnosis and treatment of EMO patients, but also provides a new idea for the prevention of mumps patients complicated with orchitis.

关 键 词：流行性腮腺炎性睾丸炎 不育症 流行性腮腺炎病毒 睾丸损伤 

分 类 号：R698[医药卫生—泌尿科学]