NLR和PLR在亚急性甲状腺炎中的诊断价值分析  

Diagnostic Value of NLR and PLR in Subacute Thyroiditis

作　　者：魏雪芳 杨煜 WEI Xuefang;YANG Yu(Department of Endocrinology,Fuzhou Second Affiliated Hospital of Xiamen University,Fuzhou Fujian 350007,China;Department of Cadre Health,Fuzhou Second Affiliated Hospital of Xiamen University,Fuzhou Fujian 350007,China)

机构地区：[1]厦门大学附属福州第二医院内分泌科,福建福州350007 [2]厦门大学附属福州第二医院干部保健科,福建福州350007

出　　处：《中国卫生标准管理》2022年第1期62-65,共4页China Health Standard Management

摘　　要：目的评估中性粒细胞/淋巴细胞比(neutrophil-to-lymphocyte ratio,NLR)和血小板/淋巴细胞比(platelet-to-lymphocyte ratio,PLR)对亚急性甲状腺炎(subacute thyroiditis,SAT)患者的诊断价值。方法选取2016年1月-2020年1月于医院内分泌科就诊的SAT患者(76例)作为亚急性甲状腺炎组(SAT组),同时选取在医院体检中心体检的健康人群(80例)作为正常对照组(NC组)。分析两组的甲状腺功能、甲状腺体积、C反应蛋白(C-reactive protein,CRP)、红细胞沉降率(erythrocyte sedimentation rate,ESR)、NLR、PLR等。结果SAT组CRP、ESR、NLR、PLR以及甲状腺体积均高于NC组,差异有统计学意义(P<0.05)。相关分析表明,在SAT患者中,NLR和PLR与CRP呈正相关(r=0.439、0.518,P<0.001),与ESR也均呈正相关(r=0.383、0.497,P<0.001);NLR和PLR与甲状腺体积(V)呈正相关(r=0.178、0.209,P<0.05)。结论SAT患者的NLR和PLR水平与健康人群有显著差异,使用NLR与PLR对SAT的诊断具有一定的临床价值,可作为SAT的诊断指标。Objective To investigate the value of neutrophil-to-lymphocyte ratio(NLR)and platelet-to-Iymphocyte ratio(PLR)for diagnosing subacute thyroiditis(SAT).Methods Patients with SAT from January 2016 to January 2020 were selected as subacute thyroiditis group(SAT group),who were treated in endocrinology department of our hospital(76 cases).While healthy people(80 cases)who underwent physical examination at our physical examination center were selected as the normal control group(NC group).Analyses were made of thyroid function tests,thyroid volume,C-reactive protein(CRP),erythrocyte sedimentation rate(ESR),NLR,PLR were compared between two groups.Results The ESR,CRP,NLR,thyroid volume and PLR were significantly higher in the SAT patients compared with NC group,the difference was statistically significant(P<0.05).Correlation analysis showed that NLR and PLR were positively correlated with CRP in SAT patients(r=0.439,0.518,P<0.001),and NLR and PLR were positively correlated with ESR(r=0.383,0.497,P<0.001).NLR and PLR were also positively correlated with thyroid volume(r=0.178,0.209,P<0.05).Conclusion The levels of NLR and PLR of SAT patients are significantly different from those of healthy people.The use of NLR and PLR for the diagnosis of SAT has certain clinical value and can be used as a diagnostic indicator of SAT.

关 键 词：中性粒细胞/淋巴细胞 血小板/淋巴细胞 亚急性甲状腺炎 诊断 血常规 红细胞沉降率 

分 类 号：R446[医药卫生—诊断学]