A water-soluble β-glucan improves growth performance by altering gut microbiome and health in weaned pigs  

作　　者：Yuliang Wu Xue Li Hongnan Liu Yanjun Du Jian Zhou Lijun Zou Xia Xiong Huilin Huang Zhiliang Tan Yulong Yin 

机构地区：[1]Hunan Province Key Laboratory of Animal Nutritional Physiology and Metabolic Process,Key Laboratory of Agro-Ecological Processes in Subtropical Region,Institute of Subtropical Agriculture,National Engineering Laboratory for Pollution Control and Waste Utilization in Livestock and Poultry Production,Scientific Observing and Experimental Station of Animal Nutrition and Feed Science in South-Central,Institute of Subtropical Agriculture,Chinese Academy of Sciences,Changsha,410125,Hunan,China [2]Sichuan Synlight Biotech Ltd.,Chengdu,610041,China [3]University of Chinese Academy of Sciences,Beijing,China [4]Laboratory of Basic Biology,Hunan First Normal University,Changsha,410205,China [5]Hunan Co-Innovation Center for Utilization of Botanical Functional Ingredients,Changsha,410128,China

出　　处：《Animal Nutrition》2021年第4期1345-1351,共7页动物营养（英文版）

基　　金：supported by National Key Research and Development Program of China(2018YFD0501100);Science and Technology Program of Changsha(kq2004078);Science and technology program of Changsha(kq1907074);the Innovation Team of Key areas of the Ministry of Science and Technology;the Science and Technology Leadership Program of Hunan Province(2019RS3021);Sichuan Synlight Biotech Ltd and Research Foundation of Education Bureau of Hunan Province,China(18B476)。

摘　　要：Beta-glucan has been shown to have a beneficial effect on gastrointestinal health.This experiment was conducted to investigate the effects ofβ-glucan isolated from Agrobacterium sp.ZX09 on growth performance and intestinal health of weaning pigs.A total of 108 weaned pigs(21 d of age;6.05±0.36 kg)were randomly divided into 3 groups(6 pens/group;6 pigs/pen),and the groups were each treated with the following diets:1)basal diet,2)basal diet supplemented with 20 mg/kg olaquindox,3)basal diet supplemented with 200 mg/kgβ-glucan,for 21 d.Compared with the control group,pigs fed with200 mg/kgβ-glucan had greaterBW,average daily gain and duodenal villus height to crypt depth ratio(P<0.05).Olaquindox increased the duodenal or jejunal villus height of pigs compared withβ-glucan.Compared with the control group,β-glucan tended to increase the occludin mRNA expression in the jejunum(0.05<P<0.10).Beta-glucan enriched the beneficial microbiota in the ileum of pigs(P<0.05).In conclusion,β-glucan may promote growth performance by improving intestinal health and increasing beneficial microbiota of weaned pigs.The study results will provide valuable theoretical guidance for the utilization ofβ-glucan in weaned pigs.

关 键 词：BETA-GLUCAN Small intestine Weaned pig 

分 类 号：S828.5[农业科学—畜牧学]