老年冠状动脉慢血流患者的影响因素分析  

Influencing factors in elderly coronary slow flow patients

作　　者：杨倩倩[1] 周鲁 宓宝斌[1] 齐洁[1] 张艳芳 胡孟芬 崔建国[1] 安可英[1] 张清潭[1] Yang Qianqian;Zhou Lu;Mi Baobin;Qi Jie;Zhang Yanfang;Hu Mengfen;Cui Jianguo;An Keying;Zhang Qingtan(Department of Geritrics,Affiliated Hospital of Binzhou Medical College,Binzhou 256600,Shandong Province,China)

机构地区：[1]滨州医学院附属医院老年医学科,256600 [2]滨州市人民医院妇产科

出　　处：《中华老年心脑血管病杂志》2022年第2期163-166,共4页Chinese Journal of Geriatric Heart,Brain and Vessel Diseases

摘　　要：目的探讨老年冠状动脉慢血流(CSF)患者的临床影响因素。方法从2017年1月~2019年8月于滨州医学院附属医院行冠状动脉造影检查的1260例患者中,选择年龄≥60岁的冠状动脉无明显狭窄患者286例,将CSF的98例作为CSF组,血流正常的188例作为对照组。回顾性分析2组患者临床资料,用相关性分析,采用多因素logistic回归分析CSF的影响因素。结果 2组性别、吸烟、嗜碱性粒细胞、红细胞、血红蛋白、平均红细胞血红蛋白浓度、红细胞比容、白蛋白、总胆汁酸、乳酸脱氢酶、活化部分凝血活酶时间、凝血酶时间、纤维蛋白原/白蛋白比较,差异均有统计学意义(P<0.05,P<0.01);相关性分析显示,红细胞(r=0.167,P=0.005)、血红蛋白(r=0.177,P=0.003)、平均红细胞血红蛋白浓度(r=0.135,P=0.022)、嗜碱性粒细胞(r=0.192,P=0.001)、白蛋白(r=-0.161,P=0.006)、总胆汁酸(r=-0.142,P=0.016)、乳酸脱氢酶(r=-0.143,P=0.015)、凝血酶时间(r=-0.141,P=0.017)、纤维蛋白原/白蛋白(r=0.184,P=0.002)与CSF组3支血管血流帧数明显相关。多因素logistic回归分析显示,总胆汁酸、白蛋白、纤维蛋白原/白蛋白是CSF患者的独立影响因素(P<0.05,P<0.01)。结论总胆汁酸、白蛋白、纤维蛋白原/白蛋白是老年CSF患者的影响因素。Objective To study the clinical influencing factors in elderly coronary slow flow(CSF) patients.Methods Two hundred and eighty-six patients aged 60 years without severe coronary artery stenosis selected from 1260 patients who underwent CAG in our hospitial from January 2017 to August 2019 were divided into CSF group(n=98) and control(normal coronary artery flow) group(n=188).Their clinical data were retrospectively analyzed.The influencing factors in CSF patients were analyzed by correlation analysis and logistic regression analysis respectively.Results Significant difference was detected in gender, history of smoking, basophils, erythrocytes, hemoglobin, mean erythrocyte hemoglobin concentration, hematocrit, albumin, total bile acid, lactate dehydrogenase, activated partial thromboplastin time, thrombin time, and fibrinogen/albumin ratio(FAR) between the two groups(P<0.05,P<0.01).Correlation analysis showed that erythrocytes, hemoglobin, mean erythrocyte hemoglobin concentration, basophilic granulocytes, albumin, total bile acid, lactate dehydrogenase, thrombin time, and FAR were closely related with the average blood flow frame number of 3 coronary arteries(r=0.167,0.177,0.135,0.192,-0.161,-0.142,-0.143,-0.141,0.184,P<0.05,P<0.01).Multivariate logistic regression analysis displayed that total bile acid, albumin and FAR were independent influencing factors in elderly CSF patients(P<0.05,P<0.01).Conclusion Total bile acid, albumin and FAR are the influencing factors in elderly SCF patients.

关 键 词：冠状血管 血流速度 胆汁 白蛋白类 纤维蛋白原 

分 类 号：R543.3[医药卫生—心血管疾病]