聚合物纳米粒子的研究进展  

Research Progress of Polymer Nanoparticles

作　　者：张晓璐 吕邵娃[1] 李永吉[1] ZHANG Xiao-lu;Lü Shao-wa;LI Yong-ji(Heilongjiang University of Chinese Medicine,Harbin 150040,China)

机构地区：[1]黑龙江中医药大学,黑龙江哈尔滨150040

出　　处：《精细化工中间体》2021年第6期1-5,共5页Fine Chemical Intermediates

基　　金：黑龙江中医药大学科研基金项目(2018xy04)。

摘　　要：随着聚合物科学和纳米技术的进步,聚合物纳米粒子已经有了巨大的发展。近年来,聚合物纳米粒子因其制备和设计简单、生物相容性好、结构多样性而被广泛应用于工程和生物材料中。聚合物纳米粒子具有更大的表面积,可存在大量的表面官能团(如配体)。这种纳米粒子的毒性低,尺寸大小可控。综述了聚合物纳米粒子与其制备技术,用于制备它们的聚合物以及一些具有新型的纳米聚合物作为传递应用的载体,并对未来的发展方向进行了展望,旨在为聚合物纳米粒子的进一步研究开发提供借鉴与参考。With the progress of polymer science and nanotechnology,polymer nanoparticles have made great progress.In recent years,polymer nanoparticles have been widely used as engineering and biological materials because of their simple preparation and design,good biocompatibility and structural diversity.Polymer nanoparticles have a larger surface area and can contain a large number of surface functional groups such as ligand.The toxicity of these nanoparticles is low and the size is controllable.Therefore,this paper reviewed polymer nanoparticles and their preparation technology,the polymers used to prepare them,and some new nano polymers as transport applications,and prospected the future development direction,in order to provide reference for the further research and development of polymer nanoparticles.

关 键 词：聚合物 纳米粒子 研究进展 

分 类 号：O63[理学—高分子化学]