针药并用配合提肛运动治疗前列腺增生的疗效观察及对血清PSA、睾酮、雌二醇的影响  

Efficacy Observation of Acupuncture Combined with Medication and Levator Ani Movement for Prostatic Hyperplasia and Its Effects on Serum PSA,Testosterone,and Estradiol

作　　者：刘永存[1] 赵会谢 刘国伟[1] LIU Yongcun;ZHAO Huixie;LIU Guowei(Shijiazhuang Hospital of Traditional Chinese Medicine,Shijiazhuang 050051,China)

机构地区：[1]石家庄市中医院,石家庄050051

出　　处：《上海针灸杂志》2022年第1期5-9,共5页Shanghai Journal of Acupuncture and Moxibustion

基　　金：河北省中医药管理局科研计划项目(2020345)。

摘　　要：目的观察针药并用配合提肛运动治疗前列腺增生的临床疗效及对血清前列腺特异性抗原(PSA)、睾酮、雌二醇的影响。方法将54例前列腺增生患者随机分为对照组和观察组,每组27例。对照组予翁沥通治疗,观察组在对照组基础上予针刺配合提肛运动治疗。观察两组治疗前后前列腺液国际前列腺症状评分(IPSS)、储尿期症状评分、PSA水平、睾酮水平、雌二醇水平、白细胞计数(WBC)和前列腺体积变化,并比较两组的临床疗效及不良反应发生率。结果两组治疗后雌二醇水平高于治疗前,睾酮水平、PSA水平、WBC计数低于治疗前,IPSS和储尿期症状评分低于治疗前;与对照组比较,观察组治疗后雌二醇升高,睾酮水平、PSA水平、WBC计数和前列腺体积降低,IPSS和储尿期症状评分水平降低;差异均有统计学意义(P<0.05)。观察组总有效率显著高于对照组,差异具有统计学意义(P<0.05)。两组不良反应发生率比较,差异无统计学意义(P>0.05)。结论针药并用配合提肛运动治疗前列腺增生,疗效肯定,能够升高雌二醇水平,降低睾酮、PSA水平。Objective To observe the clinical efficacy of acupuncture combined with medication and levator ani movement in treating prostatic hyperplasia and its effects on serum prostate-specific antigen(PSA),testosterone,and estradiol.Method Fifty-four patients with prostatic hyperplasia were randomized into a control group and an observation group,with 27 cases in each group.The control group was treated with Weng Li Tong,and the observation group was given additional acupuncture and levator ani movement.The international prostatic symptom score(IPSS),urinary storage symptom score,the levels of PSA,testosterone,and estradiol,white blood cell(WBC)count,and prostate volume were observed before and after treatment.The clinical efficacy and adverse reaction rate were compared between the two groups.Result The estradiol level increased after treatment in both groups,and the levels of testosterone and PSA,WBC count,and IPSS and urinary storage symptom score decreased.Compared with the control group,the level of estradiol was higher in the observation group,and the levels of testosterone and PSA,WBC count,prostate volume,and IPSS and urinary storage symptom score were lower or smaller.The differences were statistically significant(P<0.05).The total effective rate was higher in the observation group than in the control group,and the difference was statistically significant(P<0.05).There was no significant difference in the adverse reaction rate between the two groups(P>0.05).Conclusion Acupuncture combined with medication and levator ani movement is effective in treating prostatic hyperplasia;it can up-regulate the estradiol level and down-regulate the levels of testosterone and PSA.

关 键 词：针刺疗法 提肛运动 针药并用 前列腺特异性抗原 睾酮 雌二醇 

分 类 号：R246.1[医药卫生—针灸推拿学]