心肌桥患者焦虑-抑郁和社会压力-支持度之间的相关性分析  

Association between anxiety-depression and social stress-support in patients with myocardial bridge

作　　者：杭靖宇[1] 李永光[2] 刘常远 魏钧伯[1] 韩蓓蓓[1] 金贤 唐敏 程小燕 张佳胤[3] 沈成兴 HANG Jingyu;LI Yongguang;LIU Changyuan;WEI Junbo;HAN Beibei;JIN Xian;TANG Min;CHENG Xiaoyan;ZHANG Jiayin;SHEN Chengxing(Department of Cardiology,Sixth People’s Hospital Shanghai Jiao Tong University School of Medicine,Shanghai 200233,China;不详)

机构地区：[1]上海交通大学附属第六人民医院心内科,上海200233 [2]上海交通大学附属第六人民医院心脏中心,上海200233 [3]上海交通大学附属第六人民医院放射科,上海200233 [4]上海交通大学医学院附属瑞金医院北院高血压科 [5]上海交通大学医学院附属精神卫生中心精神科 [6]上海市浦东新区精神卫生中心心理障碍科

出　　处：《上海医学》2022年第1期28-32,共5页Shanghai Medical Journal

基　　金：国家自然科学基金(81800331);上海市卫生健康委员会科研课题面上项目(201940079);上海交通大学医学院科技创新项目(16XJ21006)。

摘　　要：目的探究心肌桥患者焦虑-抑郁与社会压力-支持度的关系。方法纳入2017年8月—2018年6月经选择性冠状动脉造影或冠状动脉CTA确诊的200例心肌桥患者的临床资料。采用汉密尔顿焦虑(HAMA)量表、汉密尔顿抑郁(HAMD-17)量表、简单自测焦虑(GAD-7)量表、9项患者健康问卷(PHQ-9)、生活事件量表(LES)和社会支持评定量表(SSRS),分析不同性别和心肌桥收缩期压缩程度患者的焦虑、抑郁和社会压力的支持情况。结果女性心肌桥患者HAMA量表评分显著高于男性(P<0.05)。不同严重程度的心肌桥患者HAMA、HAMD-17、GAD-7、PHQ-9、LES和SSRS的差异均无统计学意义(P值均>0.05)。简单线性相关分析表明,焦虑与社会压力呈正相关(r=0.274,P<0.001),与社会支持呈负相关(r=-0.174,P=0.014);抑郁与社会压力呈正相关(r=0.320,P<0.001),与社会支持呈负相关(r=-0.213,P=0.003)。结论女性心肌桥患者焦虑程度高于男性心肌桥患者,减轻心肌桥患者的生活压力和增强社会支持度可改善其焦虑-抑郁的心理状况。Objective To explore evidence of the correlation between anxiety-depression and social stress-support in myocardial bridge(MB)patients.Methods From August 2017 to June 2018,two hundred patients with myocardial bridge confirmed by selective coronary angiography or CTA were enrolled in this study.Their anxiety,depression,social stress and support were investigated by using Hamilton anxiety(HAMA)scale,Hamilton depression(HAMD)-17 scale,generalized anxiety disorder(GAD)-7 scale,patient health questionnaire-9(PHQ-9)scale,life stress event scale(LES)and social support scale(SSRS).The anxiety,depression,social stress and support of patients with different genders and the degree of MB systolic compression were compared.Results HAMA scales score was significantly higher in females than that in males(P<0.05).There was no statistical difference in anxiety score,depression score,GAD-7 score,PHQ-9 score or stress response score among patients with different severities of myocardial bridge(all P>0.05).The simple linear anxiety was positively correlated with social stress(r=0.274,P<0.001),and negatively corelated with social support(r=-0.174,P=0.014).The depression was positively associated with social stress(r=0.320,P<0.001),and negatively associated with social support(r=-0.213,P=0.003).Conclusion Female patients with myocardial bridge have higher anxiety level than males.Anxiety and depression can be alleviated by the reduction of life stress and the enhancement of social support in patients with myocardial bridge.

关 键 词：心肌桥 焦虑 抑郁 社会压力 社会支持 

分 类 号：R541[医药卫生—心血管疾病]