中医药的抗肝纤维化机制与临床应用研究进展  

Research Progress of TCM Anti-hepatic Fibrosis Mechanism and Clinical Application

作　　者：苏子衡 薛文静 程军平 SU Zi-heng;XUE Wen-jing;CHENG Jun-ping(Suzhou TCM Hospital Affiliated to Nanjing University of Traditional Chinese Medicine,Suzhou Jiangsu 215000,China;The Fifth People's Hospital of Suzhou,Suzhou Jiangsu 215000,China)

机构地区：[1]南京中医药大学附属苏州市中医医院,江苏苏州215000 [2]苏州市第五人民医院,江苏苏州215000

出　　处：《抗感染药学》2021年第11期1562-1565,共4页Anti-infection Pharmacy

摘　　要：肝纤维化是指肝脏内弥漫性细胞外基质沉积而导致的肝脏间质纤维化,其在肝硬化发展过程中起关键作用,是影响慢性肝病预后的重要环节。肝纤维化的进程是可以延缓甚至逆转的,早期有效控制肝纤维化的进展可以降低肝硬化甚至肝癌的发病率。而中药在抗肝纤维化方面有着独特优势,该文综述了中药抗肝纤维化的作用机制与临床应用。Hepatic fibrosis is an interstitial fibrosis caused by diffuse extracellular matrix deposition in the liver,affecting the prognosis of chronic liver disease and leading up to liver cirrhosis.The progression of hepatic fibrosis can be delayed or even reversed.Effective control of the development of hepatic fibrosis can reduce the incidence of cirrhosis and liver cancer.Notably,Traditional Chinese Medicine has unique advantages in resisting hepatic fibrosis.This paper reviews the mechanism and clinical application of Chinese medicine against hepatic fibrosis.

关 键 词：肝纤维化 机制 临床应用 

分 类 号：R285[医药卫生—中药学]