不同脐带结扎方式对超早产儿近期结局的影响  

Effect of different cord clamping methods on short-term outcomes of extremely preterm infants

作　　者：陈春[1] 杨传忠[1] 黄智峰[1] CHEN Chun;YANG Chuanzhong;HUANG Zhifeng(Department of Neonatology,Affiliated Shenzhen Maternity and Child Healthcare Hospital,Southern Medical University,Shenzhen 518028,China)

机构地区：[1]南方医科大学附属深圳市妇幼保健院新生儿科,广东深圳518028

出　　处：《实用医学杂志》2022年第2期201-205,共5页The Journal of Practical Medicine

基　　金：深圳市“医疗卫生三名工程”资助项目资助(编号:SZSM201612045);广东省高水平临床重点专科(深圳市配套建设经费)(编号:SZGSP009)。

摘　　要：目的探讨不同延迟脐带结扎方式对孕周<28周超早产儿的影响。方法回顾性纳入南方医科大学附属深圳市妇幼保健院新生儿科2019年1月至2020年12月孕周<28周超早产儿,按照脐带结扎方式分成常规组、延迟脐带结扎组和切断脐带进行脐带挤压组。比较三组患儿住院期间有创辅助通气时长、无创辅助通气时长、入院体温、住院时间、输血次数以及脑室周围-脑室内出血、坏死性小肠结肠炎、晚发型败血症、支气管肺发育不良、早产儿视网膜病、死亡等发生率。结果延迟脐带结扎组和切断脐带挤压脐带组无创辅助通气时长、住院时间短于常规组;输血次数与脑室周围-脑室内出血、支气管肺发育不良发生率低于常规组,差异有统计学意义(P <0.05);延迟脐带结扎组与切断脐带挤压脐带组无创辅助通气时长,住院时间、输血次数及各疾病发生率,差异无统计学意义(P> 0.05)。结论延迟脐带结扎与切断脐带脐带挤压均可缩短超早产儿无创辅助通气时长、住院时间,减少住院期间输血次数,降低超早产儿脑室周围-脑室内出血和支气管肺发育不良的发生率。Objective To investigate the effect of different delayed cord clamping methods on extremely preterm infants at < 28 weeks of gestation. Methods Extremely preterm infants who were born less then 28 weeks of gestation from January 2019 to December 2020 in the Neonatology Department of Shenzhen Maternity and Child Healthcare Hospital Affiliated to Southern Medical University were retrospectively included and divided into conventional group,delayed cord clamping group,and severed cord for cord extrusion group according to the type of umbilical cord clamping. The time spent on invasive assisted ventilation,time spent on noninvasive assisted ventilation,length of stay,frequency of blood transfusions,and incidence of periventricular-intraventricular hemorrhage,necrotizing enterocolitis,late-onset sepsis,respiratory distress syndrome,bronchopulmonary dysplasia,and retinopathy of prematurity during hospitalization were compared among these three groups of infants. Results The infants in the delayed cord clamping group and the extruded cord group spent less time on invasive and noninvasive assisted ventilation and had a shorter hospital stay than those of the conventional group;the frequency of blood transfusion and the incidence of periventricular-intraventricular hemorrhage,respiratory distress syndrome,bronchopulmonary dysplasia,and retinopathy of prematurity were lower than those in the conventional group,and there were statistically significant differences(P < 0.05);The infants in the delayed cord clamping group and the extruded cord group spent less time on invasive and noninvasive assisted ventilation and had a shorter hospital stay than the those of the conventional group;the frequency of blood transfusion and the incidence of periventricularintraventricular hemorrhage,respiratory distress syndrome,bronchopulmonary dysplasia,and retinopathy of prematurity were lower than those in the conventional group,and the differences were statistically significant(P < 0.05).Conclusion Both methods,delayed cord clamping and sev

关 键 词：延迟脐带结扎 脐带 结扎术 超早产儿 

分 类 号：R722.6[医药卫生—儿科]