儿童哮喘急性发作合并血液高凝状态的研究进展  

Progress of acute attack of asthma with hypercoagulable state in children

作　　者：苏松(综述) 尹嘉宁(审校)[1] 方昕(审校) 乔红梅(审校)[1] Su Song;Yin Jianing;Fang Xin;Qiao Hongmei(Pediatric Respiratory Department 1,The First Hospital of Jilin University,Changchun 130021,China)

机构地区：[1]吉林大学第一医院小儿呼吸一科,长春130021

出　　处：《国际儿科学杂志》2021年第12期813-817,共5页International Journal of Pediatrics

基　　金：吉林省医疗卫生人才专项(JLSWSRCZX2020-024)。

摘　　要：支气管哮喘(简称哮喘)是儿童时期一种常见的气道慢性炎症性疾病,是以气道慢性炎症及气道高反应性为特征的异质性疾病。不同程度的哮喘急性发作常伴随多个系统的损伤,包括呼吸系统、循环系统、血液系统等。目前有关哮喘急性发作伴随血液高凝状态,出现血栓、肺栓塞等危及生命并发症的文献报道逐渐出现,并呈上升趋势。该文总结国内外哮喘急性发作合并血液高凝状态的相关研究进展,就发病机制、监测指标及治疗进行综述,以期早发现、早治疗,防止出现严重的并发症,降低病死率。Bronchial asthma in children is a common chronic inflammation of the lower airway.It is a heterogeneous disease characterized by chronic airway inflammation and airway hyperresponsiveness.Acute asthma attack in different degrees is often accompanied by multiple system damage,including respiratory system,circulatory system,blood system and so on.At present,the literature reports about acute attack of asthma accompanied by thrombophilia,thrombosis,pulmonary embolism and other life-threatening complications gradually appear,and show an upward trend.This paper summarizes the literature of acute asthma attack with thrombophilia at home and abroad,and reviews the pathogenesis,monitoring indicators and treatment,so as to diagnose and treat early,prevent serious complications and reduce mortality.

关 键 词：哮喘 急性发作 儿童 血液高凝状态 

分 类 号：R56[医药卫生—呼吸系统]