胎盘植入性疾病分子机制和病理诊断研究进展  

Advances in molecular mechanism and pathological diagnosis of placenta accreta spectrum disorders

作　　者：曾晚 刘从容[2] 黄欣[2] 王妍[1] ZENG Wan;LIU Cong-rong;HUANG Xin;WANG Yan(Department of Obstetrics and Gynecology,Peking University Third Hospital,Beijing 100191;Department of Pathology,Peking University Third Hospital,Beijing 100191)

机构地区：[1]北京大学第三医院妇产科,北京100191 [2]北京大学第三医院病理科,北京100191

出　　处：《生殖医学杂志》2022年第2期268-272,共5页Journal of Reproductive Medicine

基　　金：北京大学医学部-X交叉种子基金(BMU2020MX014)。

摘　　要：胎盘植入性疾病(placenta accreta spectrum disorders,PAS)是胎盘绒毛不同程度侵入子宫肌层的一组疾病。PAS是产科的高危并发症之一,在临床上可导致严重产后出血、休克、子宫切除,甚至产妇死亡。病理诊断是PAS诊断的“金标准”,但目前仍存在争议。本文主要就PAS的分子机制和病理诊断两个方面进行综述,以期提高PAS的病理诊断率。Placenta accreta spectrum disorders(PAS)are a group of diseases in which placental villous invade the myometrium on different degrees.PAS is one of the complex complications of obstetrics,which can lead to severe postpartum hemorrhage and shock,as well as hysterectomy and even maternal death.Pathological diagnosis is the“gold standard”for PAS,but there are still some controversies.This review will focus on the molecular mechanism and pathological diagnosis of PAS,and expects to improve the pathological diagnosis rate of PAS.

关 键 词：胎盘植入性疾病 组织病理学 发病机制 

分 类 号：R714.2[医药卫生—妇产科学]