Surface characterization and biocompatibility of isotropic microstructure prepared by UV laser  

作　　者：Yifei Wang Jing Zhang Kangmei Li Jun Hu 

机构地区：[1]College of Mechanical Engineering,Donghua University,Shanghai 201620,China

出　　处：《Journal of Materials Science & Technology》2021年第35期136-146,共11页材料科学技术（英文版）

基　　金：financially supported by the Fundamental Research Funds for the Central Universities(Nos.2232018A3-08,2232018D3-04);the National Natural Science Foundation of China(No.51605296);the Fundamental Research Funds for the Central Universities and Graduate Student Innovation Fund of Donghua University(No.CUSF-DH-D-2020052)。

摘　　要：To construct a structure with a structure-inducing function favors the personalized design and processing of the implant.Pulse lasers provide convenient conditions for the preparation of functional structures.The laser with a wavelength of 355 nm and pulse width of 50 ns was employed to prepare the structure with cauliflower-like(Cf),sputtered droplets(Sd),and lattice(Lt)characteristics.We analyzed the influence of laser process parameters on the formation of morphology,roughness,surface chemical composition(X-ray photoelectron spectroscopy,XPS),phase,and wettability of titanium alloys.We ascertained the proliferation and osteogenic differentiation of mesenchymal stem cells(MSCs)on Cf,Sd,and Lt structures.The results showed that multiple depositions,aggregation,and oxidation of droplets with a thick oxide layer played an essential role in forming the Cf.With the reduction of scanning speed(v)and pitch(Dy),pollutants containing O-C=O were removed,and the chemical composition of the surface gradually transformed from Ti,Ti_(2)O_(3),and TiO_(2) to complete TiO_(2).The rough Cf structure had super-hydrophilic and underwater oleophobic properties,and the near-surface was mostly rutile.Nevertheless,the high interfacial tension and fractal dimension inhibited cell adhesion and proliferation.Interestingly,the stem cells had outstanding osteogenic differentiation on the surface of the Sd structure with higher hardness(450 HV)and appropriate roughness(S_(a)=1μm).The Lt had a gradient of roughness and hardness at low laser spot overlap.Stem cells adhered and migrated to the ablation ring under locally amplified traction,and there was excellent osteogenic differentiation through mechanotransduction.

关 键 词：Laser ablation TI6AL4V Surface topography WETTABILITY BIOCOMPATIBILITY 

分 类 号：TG146.23[一般工业技术—材料科学与工程] TG665[金属学及工艺—金属材料] R318.08[金属学及工艺—金属学]