布地奈德联合特布他林雾化治疗小儿支气管肺炎的效果分析  

Clinical efficacy of budesonide combined with terbutaline on children with bronchial pneumonia

作　　者：赵金丽[1] 刘应中[2] Zhao Jinli;Liu Yingzhong(Department of Pediatrics,Taiyuan Iron and Steel Group General Hospital,the Sixth Hospital of Shanxi Medical University,Taiyuan 030003,China;Department of Nephrology,Taiyuan Iron and Steel Group General Hospital,the Sixth Hospital of Shanxi Medical University,Taiyuan 030003,China)

机构地区：[1]太原钢铁(集团)有限公司总医院山西医科大学第六医院儿科,太原030003 [2]太原钢铁(集团)有限公司总医院山西医科大学第六医院肾内科,太原030003

出　　处：《中国实用医刊》2021年第22期92-94,共3页Chinese Journal of Practical Medicine

摘　　要：目的探讨布地奈德联合特布他林雾化治疗小儿支气管肺炎的临床效果。方法抽取2017年1月至2018年12月太原钢铁(集团)有限公司总医院收治的小儿支气管肺炎102例。根据治疗药物不同分为常规组和雾化组,每组51例。比较两组临床疗效、临床症状好转时间(咳嗽消失、高热消退、气促消失、肺部湿啰音消失)以及治疗前和治疗7 d外周血嗜酸性粒细胞(EOS)水平。结果雾化组临床总有效率(96.08%)高于常规组(82.35%),P<0.05;雾化组临床症状好转的时间(咳嗽消失、高热消退、气促消失、肺部湿啰音消失)短于常规组(P<0.05);治疗7 d,雾化组患儿外周血EOS水平低于常规组(P<0.05)。治疗期间,两组均未发生严重不良反应。结论布地奈德联合特布他林治疗小儿支气管肺炎临床疗效较好,可降低患儿外周血EOS水平,缩短临床症状好转时间(咳嗽消失、高热消退、气促消失、肺部湿啰音消失),有利于患儿快速康复,且安全性较高。Objective To explore the clinical efficacy of budesonide combined with terbutaline atomization in the treatment of children with bronchopneumonia.Methods A total of 102 children with bronchopneumonia admitted to Taiyuan Iron and Steel Group General Hospital from January 2017 to December 2018 were selected.According to different drugs,they were divided into routine group and nebulization group.The clinical efficacy,the time of improvement of clinical symptoms(cough disappearance,high fever disappearance,shortness of breath disappearance,lung moist rale disappearance),and level of peripheral blood eosinophils(EOS)before and after treatment were compared between the two groups.Results The total effective rate of nebulization group was significantly higher than that of routine group(96.08%vs.82.35%,P<0.05).The time of improvement of clinical symptoms(cough disappearance,high fever disappearance,shortness of breath disappearance,lung moist rale disappearance)in nebulization group were shorter than those in routine group(P<0.05).After 7 days of treatment,the level of EOS in peripheral blood in nebulization group were significantly lower than those in routine group(P<0.05).During the treatment,no serious adverse reactions occurred in the two groups.Conclusions Budesonide combined with terbutaline has a good clinical effect in the treatment of children with bronchial pneumonia,which can significantly reduce the level of EOS in peripheral blood,shorten the time of improvement of clinical symptoms(cough disappearance,high fever disappearance,shortness of breath disappearance,lung moist rale disappearance),and is beneficial to children’s rapid recovery with high safety,which is worthy of popularization and application in the treatment of children with bronchial pneumonia.

关 键 词：布地奈德 特布他林 支气管肺炎 

分 类 号：R725.6[医药卫生—儿科]