黄芪建中汤合枳实消痞丸加减治疗脾胃虚弱型功能性消化不良的效果  

Curative Effect of Modified Huangqi Jianzhong Decoction and Zhishi Xiaopi Pills in the Treatment of Functional Dyspepsia with Weakness of Spleen and Stomach

作　　者：沈加福 谭淑芬 SHEN Jiafu;TAN Shufen(Zhao’an County Hospital,Zhao’an 363500,China)

机构地区：[1]诏安县医院,福建诏安363500

出　　处：《中外医学研究》2022年第1期67-70,共4页CHINESE AND FOREIGN MEDICAL RESEARCH

摘　　要：目的:观察黄芪建中汤合枳实消痞丸加减治疗脾胃虚弱型功能性消化不良的效果。方法:选取2019年1月-2020年12月于诏安县医院进行治疗的78例脾胃虚弱型功能性消化不良患者,按照随机数字表法将其分为对照组和观察组,每组39例。对照组采用促胃动力西药进行治疗,观察组采用黄芪建中汤合枳实消痞丸加减进行治疗。比较两组疗效及治疗前后症状的中医症候积分、幽门螺杆菌(Hp)阳性率、胃泌素含量、心理状态、生活质量。结果:治疗前,两组食欲不振、早饱、食后易泻评分比较,差异均无统计学意义(P>0.05);治疗后,观察组食欲不振、早饱、食后易泻评分均低于对照组,差异均有统计学意义(P<0.05)。治疗前,两组Hp阳性率比较,差异无统计学意义(P>0.05);治疗后,观察组Hp阳性率低于对照组,差异有统计学意义(P<0.05)。治疗前,两组胃泌素含量比较,差异无统计学意义(P>0.05);治疗后2个月,观察组胃泌素含量低于对照组,差异有统计学意义(P<0.05)。治疗前,两组HAMD、NDI评分比较,差异均无统计学意义(P>0.05);治疗后,观察组汉密尔顿抑郁量表(HAMD)、尼平消化不良指数(NDI)评分均低于对照组,差异均有统计学意义(P<0.05)。观察组总有效率为97.44%,高于对照组的79.49%,差异有统计学意义(P<0.05)。结论:黄芪建中汤合枳实消痞丸加减可有效缓解食欲不振、早饱、食后易泻的症状,降低Hp阳性率及胃泌素含量,稳定其心理状态,提高其生活质量,值得推广。Objective:To observe the curative effect of modified Huangqi Jianzhong Decoction and Zhishi Xiaopi Pills in the treatment of functional dyspepsia with weakness of spleen and stomach.Method:A total of 78 patients with functional dyspepsia of weakness of spleen and stomach treated in Zhao’an County Hospital from January 2019 to December 2020 were selected,they were divided into control group and observation group according to random number table method,39 cases in each group.The control group was treated with western medicine promoting gastric power,and the observation group was treated with modified Huangqi Jianzhong Decoction and Zhishi Xiaopi Pills.The curative effect,traditional Chinese medicine (TCM) symptom score,positive rate of Helicobacter pylori (Hp),gastrin content,psychological status and quality of life before and after treatment were compared between two groups.Result:Before treatment,there were no significant differences in scores of anorexia,early satiety and diarrhea after eating between two groups (P>0.05);after treatment,the scores of anorexia,early satiety and diarrhea after eating in the observation group were lower than those in the control group,the differences were statistically significant (P<0.05).Before treatment,there was no significant difference in Hp positive rate between two groups (P>0.05);after treatment,the Hp positive rate in the observation group was lower than that in the control group,and the difference was statistically significant (P<0.05).Before treatment,there was no significant difference in gastrin content between two groups (P>0.05);2 months after treatment,gastrin content in the observation group was lower than that in the control group,the difference was statistically significant (P<0.05).Before treatment,there were no significant differences in Hamilton depression scale (HAMD) and Nepean dyspepsia index (NDI) scores between two groups (P>0.05);after treatment,HAMD and NDI scores in the observation group were lower than those in the control group,the differences wer

关 键 词：黄芪建中汤 枳实消痞丸 脾胃虚弱 功能性消化不良 

分 类 号：R259[医药卫生—中西医结合]