Study on brain network function of the specific connection between Hégǔ(合谷LI4)and the facial-oral area  

合谷穴与面口部特异性联系的脑网络功能研究

作　　者：Hai-yan ZHOU Si-qin HUANG Xiao-wei ZHU Xiao-yi HAN Xin YANG 周海燕;黄思琴;朱晓委;韩小轶;杨馨(成都中医药大学针灸推拿学院/第三附属医院,中国四川成都610075;重庆医科大学中医药学院,中国重庆400016;重庆钢铁总医院康复科,中国重庆400081;重庆江北区中医院针灸科,中国重庆400020;成都中医药大学养生康复学院,中国四川成都610075)

机构地区：[1]College of Acupuncture and Massage/the Third Affiliated Hospital,Chengdu University of Traditional Chinese Medicine,Chengdu 610075,China [2]College of Traditional Chinese Medicine,Chongqing Medical University,Chongqing 400016,China [3]Rehabilitation Department of Chongqing Iron and Steel General Hospital,Chongqing 400081,China [4]Department of Acupuncture and Moxibustion,Jiangbei Hospital of Traditional Chinese Medicine,Chongqing 400020,China [5]College of Health Preservation and Rehabilitation,Chengdu University of Traditional Chinese Medicine,Chengdu 610075,China

出　　处：《World Journal of Acupuncture-Moxibustion》2022年第1期9-14,共6页世界针灸杂志（英文版）

基　　金：Supported by grants from National Key R&D Program of China:2019YFC1709001;the National Natural Science Foundation of China:81973959;81774435;81674068;the Foundation of Sichuan Provincial Administration of Traditional Chinese Medicine:2018JC007;the Foundation of Chengdu University of Traditional Chinese Medicine:QNXZ2018034;the National Program on Key Basic Research Project of China:2010CB530501.

摘　　要：Objective:This study was designed to observe the effect of electroacupuncture at Hégǔ(合谷L14),or Hòuxī(后溪SI3) or Wàiguān(外关TE5) acupoints on the function of the brain regions of a healthy human,and to explore the neural information mechanism of a specific connection between LI4 and the facialoral area from the point of view of the brain function connection network.A further objective was to enrich knowledge of the specific connection between the body surface and the meridian route,and the specificity of acupoint effects.Methods:A total of 30 healthy volunteers were randomly assigned to LI4,SI3,and TE5 groups.The members of each group were stimulated with electroacupuncture,and their heads were scanned using fMRI.DPARSFA 2.4 and REST 1.8 software were used for data preprocessing and statistical analysis.The paired t-test was used within group and the double sample t-test was used for two-group comparisons.Results:In healthy people,left LI4 with electroacupuncture mainly caused a decrease of the functional connection of the right orofacial motor area of the brain,which remained decreased after removing the needle.When LI4 was compared with SI3 and TE5,LI4 caused a more significant decline in the functional connection of the right side of the brain during acupuncture.Conclusions:Acupuncture at LI4 has a significant effect on the function of the face-and mouth-related areas in the brain,and there is a continuous effect.It is suggested that LI4 and the face and mouth have a specific relationship in the brain,which is most obvious during acupuncture.

关 键 词：Hégǔ(合谷lI4) Hòuxī(后溪SI3) Wàiguān(外关TE5) Functional magnetic resonance imaging(fMRI) Orofacial motor area Specific link 

分 类 号：R246[医药卫生—针灸推拿学]