AngioJet机械血栓清除术治疗急性下肢深静脉血栓形成的疗效分析  

Clinical Analysis of AngioJet Mechanical Thrombectomy in the Treatment of Acute Deep Venous Thrombosis of Lower Limbs

作　　者：王淑珍 陈菲[1] 祝志敏[1] 邱少东[1] 曾碧丹[1] WANG Shu-zhen;CHEN Fei;ZHU Zhi-min;QIU Shao-dong;ZENG Bi-dan(Department of Ultrasound,the Second Affiliated Hospital of Guangzhou Medical University,Guangzhou 510260,Guangdong Province,China)

机构地区：[1]广州医科大学附属第二医院超声科,广东广州510260

出　　处：《罕少疾病杂志》2022年第3期91-93,共3页Journal of Rare and Uncommon Diseases

基　　金：2021年度广州医科大学本科教学质量工程项目。

摘　　要：目的比较导管接触性溶栓(CDT)与AngioJet机械血栓清除术与在治疗下肢深静脉血栓形成中的临床应用效果。方法回顾性分析2018年12月至2020年12月我院收治的43例急性下肢深静脉血栓形成患者的临床资料,其中,20例接受CDT治疗(CDT组),23例患者接受AngioJet机械血栓清除术治疗(AngioJet组)。对比分析两组患者的住院时间、手术前后D-二聚体峰值、纤维蛋白原值、尿激酶用量、术后下肢消肿率及术后1月复查下肢静脉彩超所示髂股静脉通畅情况。结果AngioJet组的住院时间较CDT组短,术后消肿率较CDT组高,差异有统计学意义(P<0.05),术后CDT组的D-二聚体峰值及尿激酶用量均高于AngioJet组,差异有统计学意义(P<0.05)。结论AngioJet机械血栓清除术的临床应用效果可观,在改善下肢凝血功能、减少尿激酶用量,缩小下肢周径、缩短住院时间方面更具优势,能在一定程度上指导临床应用。Objective To compare the clinical effects of catheter contact thrombolysis(CDT)and AngioJet mechanical thrombectomy in deep vein thrombosis of lower limbs.Methods The clinical data of 43 patients with acute lower extremity deep venous thrombosis admitted to our hospital from December 2018 to December 2020 were retrospectively analyzed.Among them,20 patients received CDT therapy(CDT group)and 23 patients received AngioJet mechanical thrombus removal therapy(AngioJet group).The hospitalization time,D-dimer peak value before and after operation,fibrin value,urokinase dosage,postoperative lower limb detumescence rate and iliac femoral vein patency indicated by color Doppler ultrasound of lower limb vein were compared between the two groups.Results The hospitalization time of AngioJet group was shorter than that of CDT group,and the postoperative detumescence rate was higher than that of CDT group,with statistically significant difference(P<0.05).The peak value of D-dimer and the dosage of urokinase in CDT group were higher than that in AngioJet group,with statistically significant difference(P<0.05).Conclusion AngioJet mechanical thrombus removal has definite clinical application effect,which has more advantages in improving lower limb coagulation function,reducing urokinase dosage,reducing lower limb circumference and shortening hospitalization time,and can guide clinical application to a certain extent.

关 键 词：急性下肢深静脉血栓形成 AngioJet CDT 临床应用效果 

分 类 号：R654.4[医药卫生—外科学]