MRI纹理分析技术在孤立性纤维瘤(SFT)和血管瘤型脑膜瘤(AM)鉴别中的应用价值研究  

Study on the Value of MRI Texture Analysis in the Differential Diagnosis of Solitary Fibroma(SFT)and Hemangiomatous Meningioma(AM)

作　　者：王宝龙 赵伟[1] 丁爽[1] 罕迦尔别克·库锟 张浩天 王云玲[1] WANG Bao-long;ZHAO Wei;DING Shuang;Hanjiaerbieke·KUKUN;ZHANG Hao-tian;WANG Yunling(MR Room,the First Affiliated Hospital of Xinjiang Medical University,Urumqi 830000,Xinjiang Uyghur Autonomous Region,China)

机构地区：[1]新疆医科大学第一附属医院核磁室,新疆乌鲁木齐830000

出　　处：《中国CT和MRI杂志》2022年第3期14-17,20,共5页Chinese Journal of CT and MRI

基　　金：自治区区域协同创新专项(科技援疆计划)(202010482)。

摘　　要：目的探究应用2D MRI直方图纹理分析对孤立性纤维瘤(SFT)/血管外皮细胞瘤(HPC)与血管瘤型脑膜瘤(AM)进行鉴别诊断的临床价值。方法回顾性分析2013年6月至2021年5月经病理证实的17例SFT/HPC与29例AM患者的T_(1)WI增强图像,勾画病灶本身及内部出血、囊变和坏死区域,并进行直方图纹理参数分析,提取病灶的平均值、中位数、标准差、异质性、峰度、偏度以及熵等纹理参数,比较SFT/HPC与AM的直方图纹理参数并筛选出具有鉴别诊断价值的参数。结果SFT/HPC和AM的平均值、中位数及标准差三个参数差异具有明显统计学意义(P<0.001),其中标准差的鉴别诊断价值意义最大,其ROC曲线的AUC值为0.816,灵敏度及特异度分别为0.581和1。对平均值、中位数及峰度进行多参数联合分析,平均值结合标准差的鉴别诊断效能高于单个直方图纹理分析参数鉴别效能。结论使用增强扫描的T_(1)WI序列提取的磁共振直方图纹理参数,对鉴别SFT/HPC与AM有一定的临床意义。Objective To evaluate the clinical value of 2D MRI histogram texture analysis in the differential diagnosis of solitary fibroma(SFT)/hemangiopericytoma(HPC)and hemangiomatous meningioma(AM).Methods The T_(1)WI enhanced MRI data of 17 patients with SFT/HPC and 29 patients with AM confirmed by operation and pathology from June 2013 to May 2021 were analyzed retrospectively.the lesions themselves and the areas of hemorrhage,cystic degeneration and necrosis in the lesions were delineated,and the histogram texture parameters were analyzed,and the histogram texture parameters such as mean,median,standard deviation,heterogeneity,kurtosis,skewness and entropy were extracted.The histogram texture parameters of SFT/HPC and AM were compared and statistically analyzed,and the parameters with differential diagnosis value were selected.Results After comparing the texture parameters of T_(1)WI enhanced magnetic resonance histogram of SFT/HPC and AM,it was found that there were significant differences in mean,median and standard deviation(P<0.001).The AUC value of ROC curve was 0.816,sensitivity and specificity were 0.581 and 1,respectively.The multi-parameter joint analysis of average,median and kurtosis shows that the differential diagnosis efficiency of average combined with standard deviation is higher than that of single histogram texture analysis parameters.Conclusion The texture parameters of magnetic resonance histogram extracted by enhanced T_(1)WI sequence have certain clinical significance in distinguishing SFT/HPC from AM.

关 键 词：孤立性纤维瘤 血管外皮细胞瘤 血管瘤型脑膜瘤 纹理分析 

分 类 号：R445.2[医药卫生—影像医学与核医学] R739.4[医药卫生—诊断学]