潮气肺功能检测用于婴幼儿喘息性疾病临床价值观察  

作　　者：帅金凤[1] 黄坤玲[1] 安颖奇 安淑华[1] 李权恒[1] 郑博[1] 李金英[1] 赵清娟[1] 王艳艳[1] 

机构地区：[1]河北省儿童医院呼吸科,河北石家庄050031 [2]河北省唐山市第五医院神经内科,河北唐山063000

出　　处：《中国药业》2021年第S01期84-85,共2页China Pharmaceuticals

摘　　要：目的探讨潮气肺功能检测在喘息婴幼儿疾病中的临床价值。方法选取2015年7月至2016年7月在医院呼吸科病房住院的急性发作期喘息婴幼儿60例(喘息组)及下呼吸道感染但不伴喘息发作的婴幼儿50例(非喘息组),选取同期医院保健门诊体检健康婴幼儿50例(对照组)。将喘息组分为A1组(首次喘息组,34例)及A2组(反复喘息组,喘息发作≥2次,26例),根据有无合并症分为B1组(未合并高危因素组,35例)和B2组(合并高危因素,25例),并对其进行潮气肺功能检测。结果喘息组与非喘息组的达峰时间比(TPTEF/TE)、达峰容积比(VPEF/VE)均显著低于对照组(P<0.05),且喘息组的TPTEF/TE及VPEF/VE显著低于非喘息组(P<0.05)。急性期A1组、A2组的TPTEF/TE及VPEF/VE均显著低于对照组(P<0.05);缓解期A1组、A2组的TPTEF/TE及VPEF/VE均显著较急性期显著升高(P<0.05),但均仍显著低于对照组(P<0.05);A2组TPTEF/TE及VPEF/VE均显著低于对照组(P<0.05)。急性期B1组、B2组的TPTEF/TE及VPEF/VE均显著低于对照组(P<0.05);缓解期B1组、B2组的TPTEF/TE及VPEF/VE均较急性期显著升高(P<0.05),但均仍显著低于对照组(P<0.05);B2组的TPTEF/TE及VPEF/VE均显著低于对照组(P<0.05)。结论在临床为喘息婴幼儿开展潮气呼吸肺功能检测可为预测哮喘和指导治疗提供帮助。Objective To investigate the clinical value of tidal pulmonary function test in asthmatic infants.Methods A total of 60 infants with acute wheezing(wheezing group)and 50 infants with lower respiratory tract infection without wheezing(non-wheezing group)hospitalized in the respiratory ward of the hospital from July 2015 to July 2016 were selected.At the same time period,50 healthy infants(control group)were selected.The asthmatic group was divided into group A1(34 cases in the first asthmatic group)and group A2(26 cases in the repeated asthmatic group with≥2 asthmatic attacks).According to whether there was any combination,the asthmatic group was divided into group B1(35 cases in the group without high-risk factors)and group B2(25 cases in the group with high-risk factors),and the tidal pulmonary function was tested.Results The peak time ratio(TPTEF/TE)and peak volume ratio(VPEF/VE)of the asthmatic group and non-asthmatic group were significantly lower than those of the control group(P<0.05),and the TPTEF/TE and VPEF/VE of asthmatic group were significantly lower than those of non-asthmatic group(P<0.05).In the acute phase,TPTEF/TE and VPEF/VE in group A1 and A2 were significantly lower than those in the control group(P<0.05).TPTEF/TE and VPEF/VE in groups A1 and A2 in the remission phase were significantly higher than those in the acute phase(P<0.05),but those in groups A1 and A2 were still significantly lower than those in control group(P<0.05).TPTEF/TE and VPEF/VE in group A2 were significantly lower than those in the control group(P<0.05).TPTEF/TE and VPEF/VE in groups B1 and B2 were significantly lower than those in the control group(P<0.05);TPTEF/TE and VPEF/VE in remission group B1 and B2 were significantly higher than those in acute phase(P<0.05),but they were still significantly lower than those in control group(P<0.05).TPTEF/TE and VPEF/VE in group B2 were significantly lower than those in the control group(P<0.05).Conclusion Tidal pulmonary function test can be used to predict asthma and guide treatme

关 键 词：喘息 潮气肺功能 临床价值 

分 类 号：R443[医药卫生—诊断学]