LVIS支架辅助弹簧圈栓塞术治疗颅内动脉瘤的效果  

Effect of LVIs stent assisted coil embolization in the treatment of intracranial aneurysms

作　　者：白奕斌 冯书珍 黄永华 伍志德 唐剑锋 梁佳雄 袁东 Bai Yibin;Feng Shuzhen;Huang Yonghua;Wu Zhide;Tang Jianfeng;Liang Jiaxiong;Yuandong(Department of neurosurgery,Shaoguan first people's hospital,Shaoguan,Guangdong,512000,China)

机构地区：[1]韶关市第一人民医院神经外科,广东韶关512000

出　　处：《齐齐哈尔医学院学报》2021年第23期2051-2054,共4页Journal of Qiqihar Medical University

摘　　要：目的探讨低轮廓可视化管腔内支架(LVIS)辅助弹簧圈栓塞术治疗颅内动脉瘤的效果。方法回顾性分析2017年1月—2021年1月本院神经外科60例接受介入手术治疗的颅内动脉瘤患者临床资料,根据患者手术方案的不同将接受传统弹簧圈栓塞术治疗的29例患者纳入为对照组,将接受LVIS支架辅助弹簧圈栓塞术治疗的31例患者纳入研究组。对比两组术后即刻栓塞效果,术前与术后1 d的凝血酶原时间(PT)、血小板平均聚集率(Ara)、D-二聚体(D-D)及术后3个月的并发症发生率、复发率及栓塞程度。结果研究组栓塞有效率96.77%,高于对照组的79.31%,差异有统计学意义(χ^(2)=4.434,P<0.05);术前两组PT、D-D、Ara比较,差异无统计学意义(t=0.603、0.780、0.091,P>0.05),术后1 d研究组PT长于对照组,D-D、Ara低于对照组,差异均有统计学意义(t=4.599、12.315、5.914,P<0.05);术后3个月研究组并发症发生率为4.10%,低于对照组的31.03%,差异有统计学意义(χ^(2)=4.271,P<0.05);术后3个月研究组复发率为6.45%,对照组的复发率为20.68%,差异无统计学意义(χ^(2)=1.541,P<0.05);术后3个月研究组栓塞有效率为87.10%,高于对照组的58.62%,差异有统计学意义(χ^(2)=6.213,P<0.05)。结论采用LVIS支架辅助微弹簧圈栓塞治疗颅内动脉瘤,可进一步提高栓塞效果,对维持患者术中血流动力学稳定及降低术后并发症发生率也具有积极意义。Objective To investigate the effect of coil embolization assisted by low-profile visualization intraluminal stent(LVIS)on patients with intracranial aneurysms.Methods The clinical data of 60 patients with intracranial aneurysms who received interventional therapy in neurosurgery department of our hospital from January 2017 to January 2021 were retrospectively analyzed.According to the different surgical schemes,29 patients who received traditional coil embolization were set as the control group,and 31 patients who received LVIS stent assisted coil embolization were set as the study group.The immediate embolization effect,prothrombin time(PT),average platelet aggregation rate(ARA),and D-Dimer(D-D)at preoperative and 1 day after operation,complication rate,recurrence rate and degree of embolization at 3 months after operation were compared between the two groups.Results The effective rate of embolization in the study group was 96.77%(30/31),which was higher than 79.31%(23/29)of the control group(χ^(2)=4.434,P<0.05).There were no significant difference in PT,D-D and Ara between the two groups before operation(t=0.603,0.780,0.091,P>0.05).PT in the study group was longer than that in the control group on the 1st day after operation,and D-D and Ara in the study group were lower than those in the control group(t=4.599,12.315,5.914,P<0.05).Three months after operation,the total complication rate of the study group was 4.10%(3/31),which was lower than 31.03%(9/29)of the control group(χ^(2)=4.271,P<0.05).There was no significant difference in the recurrence rate between the study group(6.45%,2/31)and the control group(20.68%,6/29)at three months after operation(χ^(2)=1.541,P<0.05).The effective rate of embolization in the study group was 87.10%(27/31)at 3 months after operation,which was higher than 58.62%(17/29)in the control group(χ^(2)=6.213,P<0.05).Conclusions LVIS stent assisted embolization of intracranial aneurysms could further improve the embolization effect,maintain the stability of hemodynamics and reduce th

关 键 词：颅内动脉瘤 弹簧圈栓塞术 低轮廓可视化管腔内支架 并发症 

分 类 号：R651.12[医药卫生—外科学]