Preparation of quaternarized N-halamine-grafted graphene oxide nanocomposites and synergetic antibacterial properties  

作　　者：Danlin Bu Yu Zhou Chang Yang Hengyu Feng Chunxia Cheng Mengjie Zhang Zice Xu Linghan Xiao Yujing Liu Zhenai Jin 

机构地区：[1]Jilin Province Key Laboratory of Carbon Fiber Development and Application,College of Chemistry and Life Science,Changchun University of Technology,Changchun 130012,China [2]Advanced Institute of Materials Science,Changchun University of Technology,Changchun 130012,China [3]College of Materials Science and Engineering,Zhejiang University of Technology,Hangzhou 310014,China [4]Department of Pediatrics,Affiliated Hospital of Yanbian University,Yanji 133000,China

出　　处：《Chinese Chemical Letters》2021年第11期3509-3513,共5页中国化学快报（英文版）

基　　金：supported by the National Natural Science Foundation of China(No.51603020);the Jilin Province Science and Technology Natural Science Foundation Project of China(No.20180101193JC).

摘　　要：At present,frequent outbreaks of bacteria and viruses have seriously affected people's normal lives.Therefore,the study of broad-spectrum antibacterial nanocomposites is very promising.However,most antibacterial materials have some disadvantages,such as single bactericidal mechanisms and unrepeatable use.Based on the current situation,a kind of nanocomposite with three structures of graphene oxide(GO),quaternary ammonium salt(QAs)and N-halamine was prepared,which showed synergistic effect to improve antibacterial activity and combined with a variety of sterilization mechanisms.Meanwhile,GO can provide richer ways of sterilization and high specific surface area,which is conducive to the grafting of quaternarized N-halamine.The advantages of physical sterilization of GO,charge adsorption of QAs,reuse of N-halamine and efficient sterilization are fully utilized.The results showed that the quaternarized N-halamine-grafted GO was obtained successfully.GO grafted with quaternarized N-halamine polymer showed strong speedy bactericidal activity against Escherichia coli(E.coli)and Staphylococcus aureus(S.aureus)(99%).It had good storage and regeneration properties.

关 键 词：N-HALAMINE Quaternary ammonia salt Graphene oxide Synergetic sterilization Nanocomposite 

分 类 号：TB332[一般工业技术—材料科学与工程]