基于扎根理论的中成药上市后再评价专家访谈资料分析  

Analysis of Expert Interview Data on the Post-Marketing Evaluation on Chinese Patent Medicine Based on the Grounded Theory

作　　者：朱文慧 周晟 刘莉 孟庆刚 Zhu Wenhui;Zhou Shen;Liu Li;Meng Qinggang(School of Chinese Medicine,Beijing University of Chinese Medicine,Beijing 100029,China;Medical Data Analysis Center,Qingdao Ruyi Software Co.,Ltd,Qingdao 266199,China;Guizhou Hanfang Pharmaceutical Co.,Ltd,Guiyang 550081,China)

机构地区：[1]北京中医药大学中医学院,北京100029 [2]青岛如一软件有限公司医学数据分析中心,青岛266199 [3]贵州汉方药业有限公司,贵阳550081

出　　处：《世界科学技术-中医药现代化》2021年第10期3696-3703,共8页Modernization of Traditional Chinese Medicine and Materia Medica-World Science and Technology

基　　金：国家自然科学基金委员会面上项目(81973980):基于综合集成的中医药共识方法学研究,负责人:孟庆刚。

摘　　要：目的开展更全面的中成药临床应用资料收集,并对非定量化资料进行定性处理。方法运用专家深度访谈的方法,以某中成药的临床应用为例,对临床上使用过该中成药的专家进行半结构式访谈,记录并整理访谈资料,引入扎根理论方法进行访谈资料分析。结果本研究共访谈了10位专家,经扎根理论分析编码,将该中成药的临床应用编码为该药的背景、有效性、安全性、经济便宜性、依从性、临床定位6个主范畴,最终提炼出一个核心类属,并围绕这几个方面的具体信息进行详细分析。结论通过收集、整理和分析专家经验性信息,丰富了中成药上市后再评价的临床证据集,明确了已上市中成药的临床应用范围,可为后续的临床和科研研究提供证据支持,同时,专家深度访谈和扎根理论分析是对专家经验的挖掘和利用,还可应用于中医经验传承、医者诊疗思维研究等领域。本研究进行了方法探讨和实例验证,以期为后续更高阶的研究奠定基础。Objective To conduct qualitative processing of non-quantitative data,and carry out a more comprehensive collection of clinical application data of Chinese patent medicine.Methods By using the method of expert in-depth interview,taking the clinical application of a Chinese patent medicine as an example,this paper made a semi-structured interview with the experts who have used the Chinese patent medicine in clinic.The interview data were recorded and sorted out,and the grounded theory method was introduced to analyze the interview data.Results A total of 10 experts were interviewed in this study.Based on the grounded theory analysis,the clinical application of this Chinese patent medicine was coded into 6 main categories,including its background,effectiveness,safety,economical and inexpensive,compliance and clinical positioning.A core category was finally extracted,and the specific information of these aspects was analyzed in detail.Conclusion By collecting,sorting out and analyzing the empirical information of experts,the clinical evidence set of the post-marketing evaluation on Chinese patent medicine is enriched,and the clinical application scope of the Chinese patent medicine already on the market is clarified,so as to provide evidence support for subsequent clinical and scientific research.At the same time,expert in-depth interview and grounded theory analysis are the excavation and utilization of expert experience,and can also be applied to the inheritance of traditional Chinese medicine experience,medical treatment thinking research and other fields.In this study,methods are discussed and examples are verified,in order to lay a foundation for further research.

关 键 词：中成药 上市后再评价 质性研究 专家深度访谈 扎根理论 

分 类 号：R286[医药卫生—中药学]