机构地区:[1]河南省洛阳正骨医院·河南省骨科医院门诊,河南郑州450000
出 处:《黑龙江医学》2022年第2期243-245,共3页Heilongjiang Medical Journal
基 金:河南省中医药科学研究专项课题(2019ZY2157)。
摘 要:目的:分析中医隔姜灸联合个性化护理防治类风湿关节炎(RA)治疗后胃肠道反应的临床效果。方法:选取2018年3月—2020年3月河南省洛阳正骨医院诊治的120例RA患者作为研究对象,按随机数表法分成常规组和联合组,每组各60例。常规组患者进行中医隔姜灸治疗,联合组患者进行中医隔姜灸联合个性化护理防治。采用视觉模拟评分法(VAS)评估两组患者治疗前后的疼痛评分,观察两组患者治疗前后卡氏评分(KPS)、临床疗效、中医证候积分、总胆红素(TB)、碱性磷酸酶(ALP)、谷氨转氨酶(ALT)水平变化与胃肠道反应情况。结果:治疗2周、4周后,两组患者VAS评分较治疗前降低,联合组患者VAS评分低于常规组,差异有统计学意义(t=24.567、27.954,P<0.05)。联合组患者临床总有效率高于常规组,差异有统计学意义(χ^(2)=4.576,P<0.05)。两组患者中医证候积分评分较治疗前降低,联合组患者中医证候积分低于常规组,差异有统计学意义(t=30.418、27.669,P<0.05)。联合组患者胃肠道反应率低于常规组,差异有统计学意义(χ^(2)=5.132,P<0.05)。两组患者治疗前KPS评分比较,差异无统计学意义(t=0.276,P>0.05),治疗后联合组KPS评分显著低于常规组,差异有统计学意义(t=8.068,P<0.05)。两组患者治疗前ALT、ALP、TB水平比较,差异无统计学意义(t=0.246、8.249、0.072,P>0.05),治疗后联合组ALT、ALP、TB的含量显著低于常规组,差异有统计学意义(t=3.572、3.716、3.300,P<0.05)。结论:中医隔姜灸联合个性化护理干预类风湿关节炎患者,既能提升临床疗效,减少关节疼痛,又能减少胃肠道不良反应,改善中医证候积分。Objective:To investigate the effect of ginger moxibustion combined with personalized nursing in prevention and treatment of gastrointestinal tract after rheumatoid arthritis(RA)treatment.Methods:120 RA patients in the hospital from March2018 to March 2020 were enrolled,and divided into two groups by random number table methods,with 60 cases in each group.The routine group received ginger moxibustion,while the combined group received ginger moxibustion combined with personalized nursing.The visual analogue scale(VAS)was used to evaluate the pain scores of the two groups before and after treatment.The Karnofsky score(KPS),clinical efficacy,TCM syndrome score,total bilirubin(TB),alkaline phosphatase(ALP),glutaminase(ALT)levels and gastrointestinal reactions were observed before and after treatment in the two groups of patients condition.Results:After2 weeks and 4 weeks of treatment,the visual analogue scale(VAS)scores of the two groups were lower than those before treatment.After 2 weeks and 4 weeks of treatment,the VAS score of the combined group was lower than that of the routine group,and the difference was statistically significant(t=24.567,27.954,P<0.05).The total clinical effective rate of patients in the combined group was higher than that in the routine group(χ^(2)=4.576,P<0.05).After 2 weeks and 4 weeks of treatment,the scores of TCM syndrome scores in the two groups were lower than those before treatment.After 2 weeks and 4 weeks of treatment,the TCM syndrome scores of the patients in the combination group were lower than those in the conventional group(t=30.418,27.669,P<0.05).The gastrointestinal reaction rate in the combined group was lower than that in the conventional group(χ^(2)=5.132,P<0.05).There was no statistically significant difference in KPS score between the two groups before treatment(t=0.276,P>0.05).After treatment,the KPS score of the combined group was significantly lower than that of the conventional group,and the difference was statistically significant(t=8.068,P<0.05).There was no sta
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