甘露寡糖调节畜禽肠道健康机制研究进展  

Research Progress in the Regulatory Mechanism of Mannose Oligosaccharides on Intestinal Health of Livestock and Poultry

作　　者：殷运菊 马杰[1] 陈清华[1] 王兴吉 YIN Yunju;MA Jie;CHEN Qinghua;WANG Xingji(College of Animal Science and Technology,Hunan Agricultural University,Hunan Changsha 410128,China;Shandong Longkete Enzyme Preparation Co.,Ltd.,Shandong Yishui 276400,China)

机构地区：[1]湖南农业大学动物科学技术学院,湖南长沙410128 [2]山东隆科特酶制剂有限公司,山东沂水276400

出　　处：《饲料工业》2022年第2期18-21,共4页Feed Industry

基　　金：湖南省“双一流”建设专项[kxk201801004]。

摘　　要：抗生素的滥用致使畜禽肠道菌群的紊乱及耐药性的产生,同时造成环境的污染。因此,改善畜禽肠道健康是提高养殖业生产效益的重要方法,也是目前行业的重点研究方向。甘露寡糖作为一种饲料添加剂可通过影响宿主肠道形态、菌群结构、微生物多样性促进肠道健康,刺激肠道分泌甘露糖结合蛋白与病原体结合发挥吞噬作用,刺激巨噬细胞分泌细胞因子,促进T细胞的增殖分化,从而增强机体免疫功能。文章主要从甘露寡糖调节肠道健康的机制进行综述,为其在畜禽生产中的应用及推广提供参考。The abuse of antibiotics leads to the disorder of intestinal flora and the generation of drug resistance in livestock and poultry,and causes environmental pollution at the same time.Therefore,improving the intestinal health of livestock and poultry is an important method to improve the production efficiency of breeding industry,and it is also the key research direction of the industry at present.Mannose oligosaccharides as a feed additive can promote intestinal health by influencing intestinal morphology,the bacteria community structure and microbial diversity of the host;stimulate the secretion of intestinal mannose binding protein to bind with pathogens,and play a role of phagocytosis;stimulate the secretion of cell factor by macrophage,promote T cell proliferation&differentiation,thereby enhance the body’s immune function.In this paper,the mechanism of mannan oligosaccharides regulating intestinal health was reviewed to provide a reference for its application and promotion in livestock and poultry production.

关 键 词：甘露寡糖 肠道菌群 巨噬细胞 T细胞 畜禽生产 

分 类 号：S816.7[农业科学—饲料科学]