基于偶氮苯-4,4'-二羧酸衍生物的水相超分子自组装  

Supramolecular Self-Assembly of Azobenzene-4,4’-dicarboxylic Acid Derivatives in Water

作　　者：李孟微 王红言 王莹莹[1] 康晓颖 刘美芳 陈于蓝[1] LI Meng-Wei;WANG Hong-Yan;WANG Ying-Ying;KANG Xiao-Ying;LIU Mei-Fang;CHEN Yu-Lan(Tianjin Key Laboratory of Molecular Optoelectronic Science,Institute of Molecular Plus,Tianjin University,Tianjin 300354,China;College of Chemistry-Chemical&Environmental Engineering,Weifang University,Weifang 261061,China)

机构地区：[1]天津大学分子+研究院,天津市分子光电科学重点实验室,天津300354 [2]潍坊学院化学化工与环境工程学院,潍坊261061

出　　处：《应用化学》2021年第10期1362-1370,共9页Chinese Journal of Applied Chemistry

基　　金：国家重点研发计划(Nos.2017YFA0204503,2017YFA0207800);国家自然科学基金(Nos.51903187,21734006,21975178);中国博士后科学基金(No.2020 M670642)资助。

摘　　要：设计合成了两种含偶氮苯的羧酸盐(Azo-2COONa和Azo-2TBA)和一种含四苯基甲烷的甲脒盐酸盐(TPM-4Cl)。在氢键作用和静电作用的驱动下,两种羧酸盐均可与TPM-4Cl在水相发生自组装,形成具有高稳定性和高长径比的针状晶体。在该类基于羧酸-脒的超分子结构中,脒阳离子TPM^(4+)和羧酸根阴离子Azo^(2-)的结合比(n(TPM^(4+))∶n(Azo^(2-))=1∶2)可以通过傅里叶变换红外(FT-IR)光谱和核磁共振(NMR)波谱得以证实。此外,组装体的可逆形成与解组装可以通过改变水溶液的酸碱环境进行调控。因此,这一工作不仅提供了一种简单、绿色、高效的方法构筑三维超分子有序结构,也有望推动该类组装体在客体分子(如药物分子)的选择性包裹与释放方面的应用。Two azobenzene-based carboxylates(Azo-2TBA,Azo-2COONa)and a tetrapenylmethane-containing tetra-amidinium(TPM-4Cl)were designed and synthesized.Both the two carboxylates could assemble with TPM-4Cl in aqueous media through hydrogen bonding and electrostatic interaction,resulting needle-like crystals with high stability and high aspect ratio.The supramolecular structures constituted of tetra-amidinium(TPM^(4+))and carboxylates(Azo^(2-))in a molar ratio of 1∶2 were confirmed by Fourier transform infrared(FT-IR)and nuclear magnetic resonance(NMR)analysis.Additionally,it was found that the self-assembly and disassembly of assemblies could be regulated by acid or base triggers.This work not only provides a simple,green and efficient approach to construct three-dimensional ordered supramolecular structures,but also facilitates their applications in selective encapsulation and release of guests,such as small molecule drugs.

关 键 词：自组装 偶氮苯 酸响应 氢键作用 

分 类 号：O641.3[理学—物理化学]