机构地区:[1]广东省第二人民医院内分泌科,广东广州510317 [2]湘雅博爱康复医院,湖南长沙410100 [3]南方医科大学中医药学院,广东广州510515
出 处:《西部医学》2022年第2期280-283,288,共5页Medical Journal of West China
基 金:广东省中医药局科研项目(20201014)。
摘 要:目的探讨干针治疗2型糖尿病植物神经病变相关勃起功能障碍的临床疗效。方法选取2020年1月~2021年2月收治的90例2型糖尿病植物神经病变相关勃起功能障碍患者作为研究对象,据随机数字表法分为药物组(A组)、干针组(B组)、干针与药物组(C组),每组30例。所有患者均采用饮食控制和降血糖治疗。A组采用西地那非,B组采用干针疗法,C组采用西地那非与干针疗法,3组均持续治疗12周,停止治疗后继续观察4周。入院时及疗程结束后统计对比3组国际勃起功能指数(IIEF-5)分值、临床疗效、中医症状积分。记录3组不良反应发生率。结果治疗后3组IIEF-5分值比较,差异有统计学意义(P<0.05),且C组与B组IIEF-5分值均高于A组(均P<0.05);3组临床治疗总有效率比较差异有统计学意义(P<0.05),且C组与B组治疗总有效率均高于A组(P<0.05);治疗后,3组患者性欲与射精感、阳痿不举、头晕耳鸣、情志抑郁、腰膝酸软等中医症状积分均有所降低,且C组与B组各中医症状积分均低于A组,评分差异均有统计学意义(P<0.05)。治疗后4周,夫妻双方性生活满意度均较前有所增加,且C组>B组>A组,差异有统计学意义(P<0.05);3组患者的不良反应比较差异无统计学意义(P>0.05)。结论干针疗法对2型糖尿病植物神经病变相关勃起功能障碍具有较好的临床疗效,安全性较高,可在临床推广应用。Objective To observe the clinical effect of dry acupuncture on erectile dysfunction associated with type 2 diabetic autonomic neuropathy.Methods Sixty patients with type 2 diabetic autonomic neuropathy-related erectile dysfunction who were admitted from January 2020 to February 2021 were selected as the research objects.According to the random number table,they were divided into drug group(group A)and dry needle group(group B),dry acupuncture and medication group(group C),30 cases in each group.All patients were treated with diet control and hypoglycemic treatment.Group A was treated with sildenafil,group B was treated with dry acupuncture,and group C was treated with sildenafil+dry acupuncture.All three groups received continuous treatment for 12 weeks,and continued observation for 12 weeks after stopping the treatment.The scores of IIEF-5,clinical efficacy,and TCM symptom scores of the three groups were statistically compared at the time of admission and after the course of treatment.The incidence of adverse reactions in the three groups was recorded.Results After treatment,the difference of IIEF-5 scores among the three groups was statistically significant(P<0.05),and the IIEF-5 scores of group C and group B were higher than that of group A(both P<0.05).There was statistical significance in the total effective rate among the three groups(P<0.05),and the total effective rate of group C and group B was higher than that of group A(P<0.05).After treatment,scores of sexual desire,ejaculation,impotence,dizziness,tinnitus,emotional depression,lumbar and knee pain and other TCM symptoms in the three groups were decreased,and scores of TCM symptoms in group C and group B were lower than group A,the difference was statistically significant(P<0.05).4 weeks after treatment,the sexual satisfaction of both husband and wife increased compared with before,and the difference was statistically significant(P<0.05)in group C>group B>group A.Conclusion Dry needling therapy can treat erectile dysfunction associated with type 2 diab
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