脑卒中后抑郁合并认知功能障碍的磁共振灌注成像观察  

Observation of magnetic resonance perfusion imaging of post-stroke depression combined with cognitive dysfunction

作　　者：赵清河 刘学军[1] 郭永华 ZHAO Qinghe;LIU Xuejun;GUO Yonghua(Department of Radiology,Affiliated Hospital of Qingdao University,Qingdao,Shandong 266003,China;Department of Imaging,of Qingzhou People's Hospital,Qingzhou,Shandong 262500,China)

机构地区：[1]青岛大学附属医院放射科,山东青岛266003 [2]青州市人民医院影像科,山东青州262500

出　　处：《影像研究与医学应用》2022年第1期28-30,共3页Journal of Imaging Research and Medical Applications

摘　　要：目的:观察脑卒中后抑郁合并认知功能障碍的磁共振灌注成像,探讨脑卒中后抑郁症合并认知障碍的发病机制。方法:选取青岛大学附属医院2020年2月—2021年2月收治的90例脑卒中患者,根据疾病类型不同将患者分为卒中组和合并组各45例。卒中组为单纯卒中患者,合并组为脑卒中后抑郁合并认知功能障碍患者。两组均进行磁共振灌注(PWI)检查,对两组患者不同部位的相对脑血流(rCBF)值进行比较。结果:合并组双侧额叶脑、左侧颞叶和右侧基底节脑血流显著低于卒中组(P<0.05);两组患者的双侧顶叶、双侧枕叶、右侧颞叶左侧基底节和双侧小脑脑血流对比无显著差异(P>0.05)。两组均值差(-36.02845),标准误差(11.36253)比较,差异有统计学意义(P<0.05)。结论:脑卒中后抑郁合并认知功能障碍的发生和双侧额叶、左侧颞叶以及右侧基底节血流灌注减少有关。Objective To observe the magnetic resonance perfusion weighted imaging of post-stroke depression with cognitive impairment,and to explore the pathogenesis of post-stroke depression with cognitive impairment.Methods 90 cases of cerebral apoplexy patients treated in the affiliated hospital of Qingdao university from February 2020 to February 2021 were selected,depending on the type of diseases,patients can be divided into stroke group and combined group,45 cases each,stroke group for pure stroke patients,combined group for depression after stroke in patients with cognitive dysfunction patients,all patients of two groups were examined by the magnetic resonance perfusion weighted imaging(PWI),The relative cerebral blood flow(rCBF)values in different parts of the two groups were compared.Results The cerebral blood flow of the bilateral frontal lobe,left temporal lobe,and right basal ganglia of the combined group was significantly lower than that of the stroke group(P<0.05).There was no significant difference in cerebral blood flow between the two groups in bilateral parietal lobe,bilateral occipital lobe,right temporal lobe,left basal ganglia and bilateral cerebellum(P>0.05).The mean difference(-36.02845)and standard error(11.36253)between the two groups were statistically significant(P<0.05).Conclusion The occurrence of post-stroke depression combined with cognitive dysfunction is related to the decrease of blood perfusion in the bilateral frontal lobe,left temporal lobe,and right basal ganglia.

关 键 词：脑卒中 卒中后抑郁 卒中后认知障碍 磁共振灌注成像 

分 类 号：R445.2[医药卫生—影像医学与核医学]