添加益生菌对肠内营养鼻饲治疗的卧床患者营养状况及肠黏膜屏障的影响分析  

Effect of Probiotics on Nutritional Status and Intestinal Mucosal Barrier of Bed Ridden Patients with Enteral Nutrition and Nasal Feeding

作　　者：陈爱娟 CHEN Ai-juan(Community Health Service Center of Nanxing Street,Hangzhou,Zhejiang 310008)

机构地区：[1]杭州市上城区南星街道社区卫生服务中心,浙江杭州310008

出　　处：《智慧健康》2021年第26期54-56,共3页Smart Healthcare

摘　　要：目的分析添加益生菌对肠内营养鼻饲治疗的卧床患者营养状况及肠黏膜屏障的影响。方法将本院于2019年1月至2021年1月收治的长期卧床患者123例为本次研究对象,按照随机数字表法分为观察组和对照组,对比分析两组患者分别治疗后的TP、ALB、HB以及PCT水平变化、临床疗效、不良反应发生率、胃肠功能改善时间、首次排便时间。结果相较于对照组患者,观察组患者临床疗效明显更高,对比统计学差异明显(P<0.05);与对照组患者相比较,观察组患者不良反应发生率明显更低,对比统计学差异明显(P<0.05);治疗前,两组患者TP、ALB、HB以及PCT水平并无明显差异(P>0.05),治疗后,观察组患者TP、ALB、HB以及PCT水平对比统计学差异明显(P<0.05);相较于对照组,观察组患者胃肠功能改善时间以及排便时间明显更短,对比统计学差异明显(P<0.05)。结论在长期卧床需鼻饲肠内营养的患者中添加益生菌可明显提高患者临床疗效,能够显著降低患者TP、ALB、HB以及PCT水平,治疗后患者不良反应发生率明显更低,相较于常规治疗更有利于改善患者身体营养以及胃肠功能,缩短患者治疗后身体康复时间,值得临床广泛应用。Objective To analyze the effect of probiotics on nutritional status and intestinal mucosal barrier of bedridden patients with enteral nutrition and nasal feeding.Methods The 123 long-term bedridden patients who received treatment in our hospital from January 2019 to January 2021 are the subjects of this study.They are divided into observation group and control group according to the random number table method,and the changes in the levels of TP,ALB,HB and PCT,clinical efficacy,incidence of adverse reactions,gastrointestinal function improvement time,and first defecation time were compared and analyzed in the two groups of patients after treatment.Results Compared with the control group,the observation group has significantly higher clinical efficacy,and the statistical difference is significant(P<0.05).Compared with the control group,the observation group has a significantly lower incidence of adverse reactions,and the comparison is statistically significant(P<0.05).Before the treatment,there were no significant differences between the TP,ALB,HB and PCT levels in the two groups(P>0.05).After the treatment,TP,ALB,HB and PCT in the observation group(P<0.05).Compared with the control group,the gastrointestinal function improvement time and defecation time of the observation group were significantly shorter,with statistically significant differences(P<0.05).Conclusion Probiotics can significantly improve the clinical efficacy of patients with long-term bed rest and enteral nutrition by nasal feeding,and can significantly reduce the levels of TP,ALB,Hb and PCT.The incidence of adverse reactions in patients after treatment is significantly lower.Compared with conventional treatment,probiotics can improve the body nutrition and gastrointestinal function of patients,and shorten the recovery time of patients after treatment,it is worthy of wide clinical application.

关 键 词：添加益生菌 肠内营养鼻饲 长期卧床 营养状况 肠黏膜屏障 

分 类 号：R459.3[医药卫生—治疗学]