拉贝洛尔联合硫酸镁提高妊娠期高血压的临床治疗效果  

Clinical efficacy of labetalol combined with magnesium sulfate on improving pregnancy-induced hypertension in patients

作　　者：王亚丹 杜兴琴 秦灿峰 杨亚楠 WANG Yadan;DU Xingqin;QIN Canfeng;YANG Yanan(Dept.of Obstetrics and Gynecology,the Maternal&Child Health Hospital of Pingdingshan,Pingdingshan 467000,China)

机构地区：[1]平顶山市妇幼保健院妇产科,河南平顶山467000

出　　处：《华夏医学》2021年第6期80-83,共4页Acta Medicinae Sinica

摘　　要：目的:探讨拉贝洛尔联合硫酸镁治疗妊娠期高血压的效果。方法:将78例妊娠期高血压病患者随机分为对照组和联合组,每组39例,对照组用硫酸镁治疗,联合组用拉贝洛尔联合硫酸镁治疗。治疗7 d后,分析两组血压、微量尿蛋白、治疗效果和不良反应。结果:治疗后联合组血压和微量尿蛋白水平低于对照组,差异有统计学意义(P<0.05);治疗总有效率94.9%高于参照组74.4%;不良反应发生率2.56%低于对照组20.51%(P<0.05)。结论:拉贝洛尔联合硫酸镁能提高治疗妊娠期高血压的效果,可有效改善患者血压和微量尿蛋白,降低不良反应。Objective:To investigate the effect of labetalol combined with magnesium sulfate on women with pregnancy-induced hypertension.Methods:78 patients with pregnancy-induced hypertension were randomized into the control group and combined treatment group,each with 39 cases.The control group were treated with labetalol,while labetalol combined with magnesium sulfate were giving to the combined treatment group.The blood pressure,microalbuminuria level,the overall efficacy and adverse reactions were compared between both groups after 7 d treatment.Results:After treatment,the blood pressure and level microalbuminuria in the combined treatment group were lower than those in the control group,which were of statistical difference(P<0.05);the overall efficacy was 94.9%,which was higher than 74.4%of the control group;and the incidence of adverse reactions was 2.56%,lower than 20.51%of the control group(P<0.05).Conclusion:The combination of labetalol with magnesium sulfate is effective in the treatment of patients with pregnancy-induced hypertension,which can effectively improve the blood pressure and microalbuminuria level,and reduce the incidence of adverse reactions in patients.

关 键 词：拉贝洛尔 硫酸镁 妊娠期高血压 微量尿蛋白 

分 类 号：R714[医药卫生—妇产科学]