成年居民不同血压水平与糖尿病患病风险相关性  

A cross-sectional study on association of blood pressure and risk of diabetes mellitus

作　　者：范雷[1] 戚敏杰 张寒雪 李卉 李艳辉 王新杰 尚飞 冯石献[1] 康锴[1] Fan Lei;Qi Minjie;Zhang Hanxue;Li Hui;Li Yanhui;Wang Xinjie;Shang Fei;Feng Shixian;Kang Kai(Department of Chronic Non-communicable Disease Control and Prevention,Henan Provincial Center for Disease Control and Prevention(CDC),Zhengzhou 450016,China;Department of Chronic Non-communicable Disease Control and Prevention,Qixian CDC,Qixian 456750,China;Department of Chronic Non-communicable Disease Control and Prevention,Hualong CDC,Puyang 457000,China;Department of Chronic Non-communicable Disease Control and Prevention,Zhongmou CDC,Zhongmou 451450,China)

机构地区：[1]河南省疾病预防控制中心慢病所,郑州450016 [2]淇县疾病预防控制中心慢病科,鹤壁市淇县456750 [3]华龙区疾病预防控制中心慢病科,濮阳457000 [4]中牟县疾病预防控制中心慢病科,郑州市中牟县451450

出　　处：《中华健康管理学杂志》2022年第1期15-20,共6页Chinese Journal of Health Management

基　　金：国家重点研发计划(2016YF0900501);河南省科技攻关项目(182102311132);中央转移支付地方项目。

摘　　要：目的分析成年居民不同血压水平与糖尿病患病风险的关系。方法2015—2019年在河南8个县区开展心血管病高危筛查与干预工作,通过问卷调查获得人口社会学特征、生活方式和身体测量等信息,通过实验室检测获得空腹血糖和血脂。采用R 3.6.3软件分析不同血压水平与糖尿病患病的关系。结果共有120040例35~75岁常住居民纳入本研究,糖尿病检出率为23.5%。正常血压、高血压前期、高血压人群间血糖水平差异具有统计学意义(P<0.05)。多因素Logistic分析显示,与正常血压人群相比,高血压前期、高血压人群糖尿病患病风险分别增加34%(OR=1.34,95%CI:1.30~1.37)和85%(OR=1.85,95%CI:1.81~1.89)。高血压控制组糖尿病患病风险是正常血压组的1.81倍(95%CI:1.77~1.85),高血压未控制组是正常血压组的2.17倍(95%CI:2.06~2.28)。亚组分析显示糖尿病患病风险随着血压水平升高而增加的趋势未发生改变(P<0.05)。结论血压升高增加糖尿病患病风险,高血压得到控制糖尿病患病风险降低。Objective To assess the association between blood pressure and the risks of diabetes mellitus.Methods Screening and intervention were conducted from 2015 to 2019 for high-risk subjects of cardiovascular diseases in eight counties of Henan.Information on demographic characteristics,lifestyle behaviors,and anthropometric measurements were obtained via a questionnaire.Fasting blood samples were collected for blood glucose and serum lipids.The R 3.6.3 software was used to analyze the relationship between blood pressure and diabetes mellitus.Results The detection rate of diabetes mellitus was 23.5% among 120040 participants aged 35-75 years.The mean fasting blood glucose level was significantly different among normotensive,prehypertensive,and hypertensive patients.Compared to normotensive patients,prehypertension and hypertension had adjusted ORs of 34%(OR=1.34,95CI%:1.30-1.37)and 85%(OR=1.85,95CI%:1.81-1.89).The corresponding ORs were 1.81(1.77-1.85)in controlled and 2.17(2.06-2.28)in uncontrolled patients.A subgroup analysis showed the same trend,where the risk of diabetes increased with blood pressure(P<0.05).Conclusions People with elevated BP may increase their risk of diabetes,while the risk declines when BP is under control.Therefore,targeted measures should be taken to reduce the risk.

关 键 词：血压水平 高血压 糖尿病 

分 类 号：R587.1[医药卫生—内分泌] R544.1[医药卫生—内科学]