异构化制备环丙甲醛的高效绿色工艺  

EFFICIENT GREEN PREPARATION OF CYCLOPROPANALDEHYDE BY ISOMERIZATION REACTION

作　　者：黄朋勉[1] 吕彦博 赵东江 彭鹏 王梓鉴 刘祥威 黄超群 Huang Pengmian;Lv Yanbo;Zhao Dongjiang;Peng Peng;Wang Zijian;Liu Xiangwei;Huang Chaoqun(School of Chemistry and Chemical Engineering, Changsha University of Science and Technology, Changsha 410000, Hu’nan, China;Changsha Jiaqiao Biotechnology Limited Company, Changsha 410000, Hu’nan, China)

机构地区：[1]长沙理工大学化学化工学院,湖南长沙410000 [2]长沙嘉桥生物科技有限公司,湖南长沙410000

出　　处：《精细石油化工》2022年第1期23-27,共5页Speciality Petrochemicals

基　　金：湖南省教育厅资助科研项目(20A019);湖南省水生资源食品加工工程技术研究中心开放基金项目资助(2018KJY08);湖南省研究生科研创新项目(CX20200889)。

摘　　要：以2,5-二氢呋喃为原料,N,N-二乙基羟胺为阻聚剂,在羰基氯氢三(三苯基膦)钌催化下进行加压反应制备中间体2,3-二氢呋喃;然后采用以纳米催化剂ZrO_(2)/TiO_(2)/γ-酸性氧化铝的固定床催化工艺,高效异构化制备环丙甲醛,两步反应总收率达75.0%以上。研究了环丙甲醛的工业化生产工艺,考察了多种稀有金属催化剂、反应温度、压力和阻聚剂的类型及用量等因素对合成2,3-二氢呋喃的影响,并对固定床催化工艺的反应温度和催化剂进行了筛选。The intermediate 2,3-dihydrofuran was prepared in high yield with good selectivity using2,5-dihydrofuran as raw material,N,N-diethylhydroxylamine as a polymerization inhibitor,under pressure reaction catalyzed by carbonyl tris(triphenylphosphine)ruthenium.Then,2,3-dihydrofuran was efficiently isomerized to cyclopropanaldehyde in a fixed-bed process catalyzed by the nano-catalyst ZrO_(2)/TiO_(2)/γ-acidic alumina.The total yield of the two-step reaction is over 75.0%.The industrial production methods of cyclopropanaldehyde were studied.The effects of various rare metal catalysts,reaction temperature,pressure,and the type and amount of polymerization inhibitors on the synthesis of 2,3-dihydrofuran were investigated,Similarly,the effects of reaction temperature of the fixed-bed catalytic process and composite of catalysts on the synthesis of cyclopropanaldehyde have also been investigated.With the advantages of green and high efficiency,this process has broad market prospects.

关 键 词：2 5-二氢呋喃 2 3-二氢呋喃 环丙甲醛 异构化 阻聚剂 

分 类 号：O622.4[理学—有机化学]