人工流产后短效口服避孕药与雌孕激素序贯治疗对月经恢复及子宫内膜容受性影响  

Influence of short acting oral contraceptives and sequential treatment of estrogen and progesterone for treating women after abortion on their endometrial receptivity

作　　者：林红梅 LIN Hongmei(Langfang Maternal and Child Health Hospital, Langfang, Hebei Province, 065000)

机构地区：[1]河北省廊坊市妇幼保健院,065000

出　　处：《中国计划生育学杂志》2021年第12期2522-2525,共4页Chinese Journal of Family Planning

基　　金：廊坊市科技支撑计划项目(2020013066)。

摘　　要：目的:探究人工流产术后应用短效口服避孕药与雌孕激素序贯治疗对月经恢复和子宫内膜容受性的影响。方法:选取2020年4月-2020年12月本院行人工流产手术女性120例,随机数表法分为短效口服避孕药组、雌孕激素序贯组和对照组(不服用含激素类药物)各40例。比较3组术后用药后阴道出血时间、月经恢复时间、术后出血量、子宫内膜厚度、月经情况(MDQ评分)、性激素[雌二醇(E_(2))、黄体生成素(LH)、促卵泡生成素(FSH)]水平、并发症及不良反应。结果:口服避孕药组与激素序贯组阴道出血时间、月经恢复时间及术后出血量均少于对照组,子宫内膜厚度激素序贯组高于口服避孕药组及对照组,MDQ评分口服避孕药组和雌孕激素序贯组均小于对照组,血清E_(2)、LH、FSH水平口服避孕药组和激素序贯组均高于对照组,并发症总发生率口服避孕药组(5.0%)、激素序贯组(5.0%)小于对照组(17.5%)(均P<0.05);3组不良反应发生率无差异(P>0.05)。结论:人工流产术后应用短效口服避孕药与雌孕激素序贯治疗均能够明显缩短阴道出血时间、促进月经恢复,且雌孕激素序贯治疗能更好改善子宫内膜容受性。Objective:To explore the therapeutic effect on menstrual recovery of short-acting oral contraceptives and sequential treatment of estrogen and progesterone for treating women after abortion,and to study its influence on endometrial receptivity of the women.Methods:A total of 120 women who underwent abortion were selected as the research subjects between April and December 2020.These women were divided into group A(40 women had treated by short-acting oral contraceptives),group B(40 women had treated by sequential treatment of estrogen and progesterone),and group C(40 women had no treated by any hormone drug)by random number table method.The vaginal bleeding time,the menstrual recovery time,the postoperative bleeding volume,the endometrial thickness,the menstrual condition(MDQ score),the levels of sex hormones[estradiol(E_(2)),luteinizing hormone(LH),follicle stimulating hormone(FSH)],the complications and adverse reactions rates of the women were compared among the three groups.Results:The vaginal bleeding time,the menstrual recovery time,and the postoperative bleeding amount of the women in group A and group B were significantly lower than those of the women in group C.The endometrial thickness of the women in group B was significantly higher than that of the women in group A or group C.MDQ score of the women in group A and group B were significantly lower than that of the women in group C.The serum E_(2),LH,and FSH levels of the women in group A and group B were significantly higher than those of the women in group C.The total incidence of complications of the women in group A(5.0%)or group B(5.0%)was significantly lower than that(17.5%)of the women in group C(all P<0.05).There was no significant difference in the incidence of adverse reactions of the women among the three groups(P>0.05).Conclusion:Short-acting oral contraceptives and sequential treatment of estrogen and progesterone for treating the women after abortion both can significantly shorten their vaginal bleeding duration and can promote their menstr

关 键 词：人工流产术 短效口服避孕药 雌孕激素 序贯疗法 子宫修复 月经恢复 

分 类 号：R71[医药卫生—妇产科学]