复发性流产患者MCV、MCH及未成熟网织红细胞指数与妊娠结局关系  

Correlation between the values of mean corpuscular volume,mean corpuscular hemoglobin,and immature reticulocyte index of the women with recurrent spontaneous abortion and their pregnancy outcomes

作　　者：张小琴[1] 倪婕[1] 姚兰[1] 龚静亚[1] ZHANG Xiaoqin;NI Jie;YAO Lan;GONG Jingya(The Second Affiliated Hospital of Soochow University, Jiangsu Province, 215004)

机构地区：[1]苏州大学附属第二医院,215004

出　　处：《中国计划生育学杂志》2021年第12期2526-2529,共4页Chinese Journal of Family Planning

摘　　要：目的:探讨复发性流产患者血平均红细胞体积(MCV)、平均红细胞血红蛋白含量(MCH)及未成熟网织红细胞指数(IRF)与妊娠结局关系及预测价值。方法:采取前瞻性研究,纳入本院2019年1月-2021年1月确诊的复发性流产患者150例(观察组)、体检健康育龄妇女150例(对照组),检测血MCV、MCH、IRF水平并分析预测复发性流产患者妊娠结局效能。结果:观察组IRF(2.89±2.37)%、MCH(27.06±2.37 pg)低于对照组(5.39±2.69)%(29.98±2.39 pg),MCV(92.43±2.22 fL)高于对照组(88.40±2.37 fL);观察组中不良妊娠结局者IRF及MCH低于正常妊娠者,MCV高于正常妊娠者(均P<0.05)。观察组IRF、MCH水平与不良妊娠结局呈负相关,MCV与不良妊娠结局呈正相关(均P<0.05);IRF、MCV以及MCH联合检测对复发性流产不良妊娠结局有预测价值;预测阳性预测值达97.8%,IRF、MCV、MCH诊断临界值分别为2.11%、93.33fL、26.66pg。结论:复发性流产患者血清MCV、MCH、IRF水平与不良妊娠结局具有相关性,3项指标联合检测有一定预测价值。Objective:To investigate the correlation between the values of mean corpuscular volume(MCV),mean corpuscular hemoglobin(MCH),and immature reticulocyte index(IRI)of the women with recurrent spontaneous abortion(RSA)and their pregnancy outcomes,and to study their predictive values for RSA.Methods:This study was a prospective study.150 women with RSA were selected in observation group,and 150 healthy women of childbearing age were selected in control group from January 2019 to January 2021.The values of blood MCV,MCH,and IRI of the women in the two groups were measured.The value of the values of blood MCV,MCH,and IRI of the women with RSA for predicting their pregnancy outcomes was analyzed.Results:The values of IRI(2.89±2.37%),and MCH(27.06±2.37 pg)of the women in the observation group were significantly lower than those(5.39±2.69%and 29.98±2.39 pg)of the women in the control group,and the MCV value(92.43±2.22 fL)of the women in the observation group was significantly higher than that(88.40±2.37 fL)of the women in the control group.In the observation group,the values of IRI and MCH of the women with adverse pregnancy outcomes were significantly lower than those of the women with normal pregnancy outcomes,but the MCV value of the women with adverse pregnancy outcomes was significantly higher(all P<0.05).The values of IRI and MCH of the women in the observation group were negatively correlated with their adverse pregnancy outcomes,but were positively correlated with their MCV value(all P<0.05).The combined detections of IRI,MCV,and MCH had predictive value for predicting the adverse pregnancy outcomes of the women with RSA,which had higher diagnostic specificity.The critical values of the IRF value,the MCV value,and the MCH value for predicting RSA were 2.11%,93.33fL,and 26.66pg,respectively.Conclusion:The values of MCV,MCH,and IRI of the women with RSA are correlated with their adverse pregnancy outcomes.The values of the combined detections of MCV,MCH,and IRI of the women for predicting their RSA has certain

关 键 词：复发性流产 平均红细胞体积 平均红细胞血红蛋白含量 未成熟网织红细胞指数 妊娠结局 

分 类 号：R71[医药卫生—妇产科学]