短效口服避孕药和雌孕激素序贯用于人工流产术后效果比较  

Comparative study on the effect of short-acting oral contraceptives and sequential estrogen and progesterone for treating women after abortion

作　　者：徐一玲[1] 尹青[1] 熊茵 徐惠敏 张丝梅 邓建松[1] XU Yiling;YIN Qing;XIONG Yin;XU Huimin;ZHANG Simei;DENG Jiansong(Liyuan Hospital Affiliated to Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei Province, 430070)

机构地区：[1]华中科技大学同济医学院附属梨园医院,武汉430070

出　　处：《中国计划生育学杂志》2021年第10期2044-2047,共4页Chinese Journal of Family Planning

基　　金：华中科技大学院系自主创新研究基金(2016YXMS135)。

摘　　要：目的:探讨人工流产术后采用短效口服避孕药或雌孕激素序贯治疗效果。方法:前瞻性选择2019年8月—2020年8月本院行人工流产术后治疗者120例,数字表法分3组各40例。治疗Ⅰ组采用口服短效避孕药治疗,治疗Ⅱ组实施雌孕激素序贯治疗,对照组常规药物治疗且未服用含激素类药物。比较3组术后恢复情况、雌孕激素水平及并发症差异。结果:对照组、治疗Ⅰ组、治疗Ⅱ组阴道出血持续时间(8.3±2.8d、5.3±1.8d、4.2±1.2d)及出血量(62.3±15.8ml、56.3±11.8ml、52.2±10.3ml)依次降低,月经复潮时间(37.2±10.8d、30.3±8.8d、28.8±8.3d)依次降低(均P<0.05)。治疗后子宫内膜厚度治疗Ⅰ组、治疗Ⅱ组(6.4±1.3mm、7.0±1.8mm)均高于对照组(4.4±1.2mm)。雌二醇水平高于对照组、孕激素水平低于对照组,并发症发生率对照组、治疗Ⅰ组、治疗Ⅱ组(27.5%、12.5%、5.0%)依次降低(均P<0.05)。结论:人工流产术后采用短效口服避孕药或雌孕激素序贯治疗效果均较好。Objective:To investigate the effect of short-acting oral contraceptives and sequential estrogen and progesterone for treating women after abortion.Methods:A total of 120 women after abortion were divided into group A,group B,and group C(40 cases in each group)according to the random numerical table from August 2019 to August 2020.The women in group A were treated with short-acting oral contraceptives,the women in group B were given estrogen and progesterone sequential treatment,and the women in group C were not given hormone drugs except to the conventional treatment.The postoperative recovery situation,the estrogen and progesterone levels,and the complications incidence of the women were compared among the three groups.Results:The duration of vaginal bleeding of the women in group C,A,and B were 8.3±2.8d,5.3±1.8d,and 4.2±1.2d,respectively,which had decreased in turn.The postoperative blood loss of the women in group C,A,and B were 62.3±15.8ml,56.3±11.8ml,and 52.2±10.3ml,respectively,which had decreased in turn.The time of menstrual recovery of the women in group C,A,and B were 37.2±10.8d,30.3±8.8d,and 28.8±8.3d,respectively,which also had decreased in turn(all P<0.05).After treatment,the endometrial thickness of the women in group A or B was 6.4±1.3mm or7.0±1.8mm,which was significant higher than that(4.4±1.2mm)of the women in group C(P<0.05).After treatment,the estradiol level of the women in group A and group B was significant higher than that of the women in group C,while the progesterone level of the women in group A and group B was significant lower.The incidence of complications of the women in group C,A and B were 27.5%,12.5%,and 5.0%,respectively,which had decreased in turn(all P<0.05).Conclusion:Short-acting oral contraceptives and sequential estrogen and progesterone for treating women after abortion all have good effectiveness.

关 键 词：人工流产术 短效口服避孕药 雌孕激素序贯治疗 术后恢复 

分 类 号：R16[医药卫生—公共卫生与预防医学]