固冲四草汤联合低分子肝素钠治疗子宫动脉栓塞术后并发症疗效及对血清CRP、IL-6影响  

Curative effect of Guchongsicao decoction combined with low molecular weight heparin sodium for treating the complications of uterine artery embolization and its influence on their serum C-reactive protein and interleukin-6 levels

作　　者：邓翠艳 王占晖 刘玉梅 DENG Cuiyan;WANG Zhanhui;LIU Yumei(Qingdao Jiaozhou Central Hospital, Shandong Province,266300)

机构地区：[1]青岛市胶州中心医院,266300

出　　处：《中国计划生育学杂志》2021年第11期2389-2392,2397,共5页Chinese Journal of Family Planning

摘　　要：目的:探究固冲四草汤联合低分子肝素钠治疗子宫动脉栓塞术后并发症疗效及对血清C-反应蛋白(CRP)、白细胞介素-6(IL-6)影响。方法:将2018年5月-2020年9月在本院分娩出现产后出血患者60例按照治疗方式不同分为两组各30例,对照组接受子宫动脉栓塞术联合低分子肝素钠治疗,中西医组在对照组基础上联合固冲四草汤治疗。比较两组患者产后24h阴道出血量及并发症、临床疗效,血清CRP、IL-6水平,症状改善情况。结果:治疗后,中西医组产后24h阴道出血量、闭经、月经量少、栓塞后综合征等总发生率(10.0%)低于对照组(36.7%),总有效率(93.3%)高于对照组(70.0%),血清CRP、IL-6水平、中医证候积分两组治疗后均降低且中西医组低于对照组(均P<0.05)。结论:固冲四草汤联合低分子肝素钠用于子宫动脉栓塞术后,可有效降低术后并发症,提高临床疗效,减轻炎症反应,改善临床症状。Objective:To explore the curative effect of Guchongsicao decoction combined with low molecular weight heparin sodium for treating the complications of the women after uterine artery embolization and its influence on their serum C-reactive protein(CRP)and interleukin-6(IL-6)levels.Methods:60 women with postpartum hemorrhage were divided into experimental group(30 cases)and control group(30 cases)according to different treatment methods from May 2018 to September 2020.The women in the control group had received uterine artery embolization combined with low molecular weight heparin sodium for treating postpartum hemorrhage,and the women in the experimental group had received Guchongsicao decoction for treating postpartum hemorrhage except to the treatment of uterine artery embolization combined with low molecular weight heparin sodium.The postpartum vaginal bleeding volume in 24 hours and complications rate,clinical efficacy,serum CRP and IL-6 levels,and symptom improvement situation of the women were compared between the two groups.Results:After treatment,the postpartum vaginal bleeding in 24h of the women in the experimental group was significantly less than that in the control group,and the total incidence of complication(10.0%),such as amenorrhea,menorrhagia,and post-embolization syndrome of the women in the experimental group was significantly lower than that(36.7%)of the women in the control group.The total effective rate(93.3%)of the women in the experimental group was significantly higher than that(70.0%)of the women in the control group.The serum CRP and IL-6 levels,and TCM syndrome score of the women in the two groups had decreased after treatment,and which of the women in the experimental group were significantly lower than those of the women in the control group(all P<0.05).Conclusion:Guchongsicao decoction combined with low molecular weight heparin sodium used for the women with postpartum hemorrhage can effectively reduce the incidence of complications of their uterine artery embolization,can improve t

关 键 词：产后出血 子宫动脉栓塞术 低分子肝素钠 固冲四草汤 临床疗效 炎症因子 

分 类 号：R714.461[医药卫生—妇产科学]