老年患者高血压病脑出血NIHSS评分与病死率、致残率以及疾病相关耻辱感的相关性研究  

Relationship between NIHSS score and mortality,disability rate and disease-related stigma in elderly patients with hypertensive intracerebral hemorrhage

作　　者：姚凯锋 张丽华[1] Yao Kaifeng;Zhang Lihua(Department of Neurology,First People's Hospital of Nantong City,Nantong,Jiangsu,226001,P.R.China)

机构地区：[1]南通市第一人民医院神经内科,江苏南通226001

出　　处：《老年医学与保健》2022年第1期103-106,124,共5页Geriatrics & Health Care

摘　　要：目的探索美国国立卫生研究院卒中量表(national institute of health stroke scale,NIHSS)评分与高血压性脑出血老年患者病死率、致残率和疾病相关耻辱感的相关性,为该病的临床干预提供依据。方法回顾性分析2019年1月—2020年12月于南通市第一人民医院治疗的高血压性脑出血老年患者133例的临床资料。采用Superman检验评估NIHSS评分与病死率、致残率、疾病耻辱感之间的相关性,采用受试者工作特征曲线(receiver operator characteristic curve,ROC),评估NIHSS评分对病死率、致残率和疾病耻辱感的预测诊断效能。结果相关性分析表明,老年高血压性脑出血患者的NIHSS评分与患者的病死率(r=0.677,P<0.001)、致残率(r=0.486,P<0.001)和耻辱感正相关(r=0.395,P<0.001)。NIHSS评分对患者病死率的预测ROC曲线下面积为0.897 (P<0.001),最佳截断值为14分,敏感度为85.19%,特异度为86.08%。NIHSS评分对患者致残率的预测ROC曲线下面积0.782 (P<0.001),最佳截断值为10分,敏感度为73.53%,特异度为71.11%。NIHSS评分对患者疾病耻辱感的预测ROC曲线下面积0.783(P<0.001),最佳截断值为11分,敏感度为75.00%,特异度为71.43%。结论 NIHSS评分与高血压性脑出血老年患者病死率、致残率和疾病相关耻辱感正相关,可望用于患者的病死率、致残率和疾病相关耻辱感的预测诊断,效能良好。Objective To explore the relationship between National Institute of Health Stroke Scale(NIHSS score and mortality,disability rate and disease-related stigma in elderly patients with hypertensive intracerebral hemorrhage and provide a basis for clinical intervention of the disease. Methods The clinical data of133 elderly patients with hypertensive intracerebral hemorrhage treated in First People’s Hospital of Nantong City from January2019 to December2020 were analyzed retrospectively. Superman test was used to evaluate the correlation between NIHSS score and mortality,disability rate and disease stigma. Receiver operator characteristic curve(ROC)was used to evaluate the predictive diagnostic efficacy of NIHSS score on mortality,disability rate and disease-related stigma. Results Correlation analysis showed that NIHSS score of elderly patients with hypertensive intracerebral hemorrhage was positively correlated with mortality(r= 0.677,P< 0.001),disability rate(r= 0.486,P< 0.001)and stigma(r= 0.395,P< 0.001). The area under ROC curve of NIHSS score in predicting mortality was0.897(P< 0.001),the optimal cut-off value of NIHSS score was14 points,the sensitivity was85.19%,and the specificity was86.08%. The area under ROC curve of NIHSS score in predicting disability rate was0.782(P< 0.001),the optimal cut-off value of NIHSS score was10 points,the sensitivity was73.53%,and the specificity was71.11%. The area under ROC curve of NIHSS score in predicting disease-related stigma was0.783(P<0.001),the optimal cut-off value of NIHSS score was11 points,the sensitivity was75.00%,the specificity was71.43%. Conclusion NIHSS score is positively correlated with mortality,disability rate and disease-related stigma in elderly patients with hypertensive intracerebral hemorrhage. It can be used for the predictive diagnosis of mortality,disability rate,and diseaserelated stigma of the patients,and the diagnostic performance is good.

关 键 词：老年 高血压性脑出血 美国国立卫生研究院卒中量表 病死率 致残率 耻辱感 

分 类 号：R544.1[医药卫生—心血管疾病] R743.34[医药卫生—内科学]