左心室多位点起搏在非特异性室内传导阻滞伴低射血分数心力衰竭患者治疗中的应用  

The application of left ventricular multipoint pacing in patients with heart failure complicated by nonspecific intraventricular block and reduced left ventricular ejection fraction

作　　者：翁俊飞 董薇 刘雷雷 杜兴祥 刘茜 彭景添[1] 郑泽琪[1] 彭小平[1] WENG Junfei;DONG Wei;LIU Leilei;DU Xingxiang;LIU Qian;PENG Jingtian;ZHENG Zeqi;PENG Xiaoping(Department of Cardiovascular Medicine,First Affiliated Hospital of Nanchang University,Nanchang,Jiangxi Province 330006,China)

机构地区：[1]南昌大学第一附属医院心血管内科,330006

出　　处：《介入放射学杂志》2022年第1期14-18,共5页Journal of Interventional Radiology

基　　金：国家自然科学基金(82060067)。

摘　　要：目的探讨左心室多位点起搏(MPP)在治疗非特异性室内传导阻滞伴低左心室射血分数(LVEF)心力衰竭患者中的应用及其疗效。方法2017年至2019年南昌大学第一附属医院诊断为非特异性室内传导阻滞伴低LVEF心力衰竭患者3例,均在局部麻醉下行有MPP功能的起搏器植入术。结果3例患者手术顺利,术中起搏器参数均较理想,无并发症发生。术后随访显示3例患者心脏面积缩小,氨基末端B型利钠肽原(NT-proBNP)明显下降,LVEF、6分钟步行距离明显上升,胸闷、气喘等症状明显好转。结论对于非特异性室内传导阻滞伴低LVEF的心力衰竭患者,MPP是一种疗效较好的治疗方法。Objective To discuss the application of left ventricular multipoint pacing(MPP)in treating patients with heart failure complicated by nonspecific intraventricular block and reduced left ventricular ejection fraction(LVEF),and to evaluate its curative effect.Methods From 2017 to 2019 at the First Affiliated Hospital of Nanchang University of China,heart failure complicated by nonspecific intraventricular block and reduced LVEF was diagnosed in three patients.All the three patients received the implantation of pacemaker carrying MPP functions under local anesthesia.Results The implantation of pacemaker was smoothly accomplished.During the operation,all the pacemaker parameters were ideal and satisfactory,and no complications occurred.Postoperative follow-up check showed that in all three patients the heart area was reduced and the amino terminal pro-B-type natriuretic peptide(NT-proBNP)level declined dramatically,while LVEF and 6-minute walk distance were prominently increased,and the symptoms of chest tightness and gasping were obviously improved.Conclusion For patients with heart failure complicated by nonspecific intraventricular block and reduced LVEF,implantation of pacemaker carrying MPP functions is an effective treatment.(J Intervent Radiol,2022,31:14-18)

关 键 词：左心室多位点起搏 非特异性室内传导阻滞 心脏再同步治疗 心力衰竭 

分 类 号：R541[医药卫生—心血管疾病]