原子荧光法测定化妆品中砷的不确定度评定  

Evaluation of Measurement Uncertainty for Determination of Arsenic in Cosmetics by Hydride Atomic Fluorescence Spectrometry

作　　者：曹菲斐 石兴红 庞学斌 程如雾 邱颖姮 邬晓鸥 CAO Fei-fei;SHI Xing-hong;PANG Xue-bin;CHENG Ru-wu;QIU Ying-heng;WU Xiao-ou(NMPA Key Laboratory for Monitoring and Evaluation of Cosmetics,Shenzhen Institute for Drug Control,Guangdong Shenzhen 518057,China)

机构地区：[1]深圳市药品检验研究院,国家药品监督管理局化妆品监测评价重点实验室,广东深圳518057

出　　处：《广州化工》2022年第3期100-102,共3页GuangZhou Chemical Industry

摘　　要：采用微波消解法处理样品、氢化物原子荧光光度法测定化妆品中砷的含量,并根据《JJF1059.1-2012测量不确定度评定与表示》建立数学模型,对上述方法的不确定度进行分析评定。经计算,其测量不确定度主要来源于标准曲线拟合及测量重复性,而称样及稀释过程引入的不确定度则较小;因此,为降低不确定度,提高结果准确性,需定期对仪器进行确认,以保证仪器处于稳定良好的状态。The sample was treated by microwave digestion and the content of arsenic in cosmetics was determined by hydride atomic fluorescence spectrometry. A mathematical model was established according to JJF1059.1-2012 Evaluation and Expression of Uncertainty in Measurement, the uncertainty of the above methods was analyzed and evaluated. The uncertainty of measurement was mainly derived from the fitting and measurement repeat ability of standard curve, while the uncertainty introduced in the weighing sample and dilution process was smaller. Therefore, in order to reduce the uncertainty and improve the accuracy of the results, the instrument should be confirmed regularly to ensure the instrument is in a stable and good state.

关 键 词：氢化物原子荧光光度法 化妆品 砷含量 不确定度 

分 类 号：TQ658.2[化学工程—精细化工]