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作 者:朱征 何秋蓉 李慧 马宇 ZHU Zheng;HE Qiurong;LI Hui;MA Yu(West China School of Public Health/West China Fourth Hospital,Sichuan University,Chengdu,Sichuan 610041,China)
机构地区:[1]四川大学华西公共卫生学院/四川大学华西第四医院,四川成都610041
出 处:《国际检验医学杂志》2022年第4期497-501,共5页International Journal of Laboratory Medicine
摘 要:目的探讨长期低剂量医用电离辐射对医疗机构医用放射工作人员外周血细胞的影响。方法选取2016-2020年在该院进行在岗期间放射作业职业病健康体检的四川省各级医疗机构医用放射工作人员为医用放射组(642例),同时选取2016-2020年在该院进行职业健康体检的非放射作业人员为对照组(636例);对两组5年间血常规检查结果进行比较。结果医用放射组白细胞计数(WBC)、中性粒细胞计数(Neu)、淋巴细胞计数(Lym)、红细胞计数(RBC)、血红蛋白(Hb)、血细胞比容(Hct)、血小板计数(PLT)和平均血小板体积(MPV)的年度间差异有统计学意义(P<0.05)。对照组RBC、Hb、Hct、MPV的年度间差异有统计学意义(P<0.05);WBC、Neu、Lym、PLT的年度间差异无统计学意义(P>0.05)。医用放射组和对照组比较,2016、2017年WBC差异有统计学意义(P<0.05);2018年WBC、PLT差异有统计学意义(P<0.05);2019、2020年,WBC、RBC、Hb、PLT差异均有统计学意义(P<0.05)。医用放射组各年度间WBC、RBC、Hb、PLT异常率差异有统计学意义(P<0.05),呈逐年上升趋势;对照组各年度间WBC、RBC、Hb、PLT异常率差异无统计学意义(P>0.05)。结论长期低剂量医用电离辐射会对医疗机构医用放射工作人员的外周血细胞产生影响,且不同类型血细胞及其相关参数的变化规律不同。Objective To investigate the effect of long-term low-dose medical ionizing radiation on peripheral blood cells of radiation workers in medical institutions.Methods The radiation workers of medical institutions at all levels in Sichuan Province undergoing the occupational health examination during the post in this hospital during 2016-2020 were selected as the medical radiation group(642 cases).At the same time,the non-radiation workers undergoing the occupational health examination in this hospital during 2016-2020 were selected as the control group(636 cases).The blood routine examination results during these 5 years were compared between the two groups.Results In the medical radiation group,the annual differences of WBC,Neu,Lym,RBC,Hb,Hct,PLT and MPV were statistically significant(P<0.05).In the control group,the annual differences of RBC,Hb,Hct and PLT were statistically significant(P<0.05),the annual differences of WBC,Neu,Lym,and PLT were not statistically significant(P>0.05).The comparison between the medical radiation group and the control group showed statistically significant differences in WBC in 2016 and 2017(P<0.05);there were statistically significant differences in WBC and PLT during 2018(P<0.05);WBC,RBC,Hb and PLT had statistically significant differences in 2019 and 2020(P<0.05).The annual abnormal rates of WBC,RBC,Hb and PLT in the medical radiation group had statistically significant differences(P<0.05)and showed the increasing trend year by year.The annual abnormal rates of WBC,RBC,Hb and PLT in the control group had no statistically significant difference(P>0.05).Conclusion Long term low-dose medical ionizing radiation will affect the peripheral blood cells of radiation workers in medical institutions,moreover the change rules of different types of blood cells and related parameters are different.
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