基于“态靶思维”探讨中医论治甲状腺相关眼病  

Discussion on treatment of thyroid associated ophthalmopathy based on"state-target theory"with Traditional Chinese Medicine

作　　者：韩笑[1] 王秀阁[1] HAN Xiao;WANG Xiuge(Affiliated Hospital of Changchun University of Traditional Chinese Medicine,Changchun 130021,China)

机构地区：[1]长春中医药大学附属医院,长春130021

出　　处：《中国中医眼科杂志》2022年第1期53-56,共4页China Journal of Chinese Ophthalmology

基　　金：吉林省中医代谢性疾病临床医学研究中心建设项目(YDZJ202102CXJD072);吉林省名老中医药专家传承工作室建设项目(吉中医药[2020]51号);吉林省中医药科技项目(2021023)。

摘　　要：甲状腺相关眼病(TAO),主要是毒性弥漫性甲状腺肿(Graves病)累及眼部的表现,以突眼、软组织炎症、眼睑挛缩、角膜溃疡、眼球运动受限、视神经损伤为主要临床特征,甲状腺功能减退、桥本甲状腺炎等疾病也可并发。TAO不仅影响患者容貌,而且并发暴露性角膜炎、复视、视神经压迫、视力损害等,严重影响患者的生存质量。现代医学多采用糖皮质激素、免疫抑制剂治疗,存在一定的毒副作用。近年来,中医药治疗在改善症状及降低药物毒副作用方面有一定优势。“态靶辨治”理论由仝小林院士提出,倡导宏观调态,微观定靶,本文基于“态靶思维”探讨TAO的中医论治,为TAO的临床诊疗提供思路。Thyroid associated ophthalmopathy(TAO)is mainly the manifestation of toxic diffuse goiter(Graves disease)involving the eyes,characterized by exophthalmos,soft tissue inflammation,eyelid contracture,corneal ulcer,limited eye movement and optic nerve injury.Hypothyroidism,Hashimoto's thyroiditis and other diseases can also be complicated.TAO not only affects the appearance of patients,but also is complicated with exposure keratitis,diplopia,optic nerve compression,visual impairment,and so on,which seriously affects the quality of life of patients.Glucocorticoids and immunosuppressants are often used in modern medicine.However,they have certain side effects.In recent years,Traditional Chinese Medicine(TCM)has shown certain advantages in improving symptoms and reducing side effects.“State-target theory”was put forward by academician TONG Xiaolin,who advocated macro-state adjustment and micro-target setting.This paper discusses the TCM treatment of thyroid eye disease based on"state-target theory",so as to provide ideas for the clinical diagnosis and treatment of TAO.

关 键 词：甲状腺相关眼病 突眼 GRAVES病 中医探讨 态靶论治 

分 类 号：R276.7[医药卫生—中医五官科学]