重组人干扰素α2b雾化吸入联合远红外止咳贴治疗小儿毛细支气管炎的临床效果  

Clinical effect of Recombinant Human Interferonα2b atomization inhalation combined with Yuanhongwai Zhike Plaster in the treatment of children with bronchiolitis

作　　者：庞宗钦 PANG Zongqin(Department of Pediatrics,Yulin Maternal and Child Health Hospital,Guangxi Zhuang Autonomous Region,Yulin 537000,China)

机构地区：[1]广西壮族自治区玉林市妇幼保健院儿科,广西玉林537000

出　　处：《妇儿健康导刊》2022年第1期42-44,62,共4页JOURNAL OF WOMEN AND CHILDREN'S HEALTH GUIDE

摘　　要：目的观察重组人干扰素α2b雾化吸入联合远红外止咳贴治疗毛细支气管炎的效果。方法选取2018年3月至2020年3月玉林市妇幼保健院收治的80例毛细支气管炎患儿,采用随机数字表法分为观察组与对照组,每组各40例。对照组给予常规综合治疗,观察组在常规综合治疗的基础上给予氧气驱动雾化吸入α2b干扰素联合远红外止咳贴治疗。比较两组治疗后的临床疗效、临床症状消失时间、住院时间以及肺部功能。结果观察组临床总有效率高于对照组,差异有统计学意义(P<0.05);观察组喘憋消失时间、咳嗽消失时间、肺部啰音消失时间、体温恢复正常时间、住院时间均短于对照组,差异有统计学意义(P<0.05);观察组治疗后潮气量、达峰时间比、达峰容积比均高于对照组,差异有统计学意义(P<0.05)。结论雾化吸入干扰素α2b联合远红外止咳贴治疗毛细支气管炎对提高治疗有效率,缩短临床症状消失时间、住院时间,改善肺功能具有重要作用,值得临床推广使用。Objective To observe Recombinant Human Interferonα2b atomization inhalation combined with Yuanhongwai Zhike Plaster in the treatment of bronchiolitis.Methods A total of 80 children with bronchiolitis diagnosed in Yulin Maternal and Child Health Hospital from March 2018 to March 2020 were selected and divided into the observation group and the control group according to random number table method,40 cases in each group.The control group was given routine comprehensive treatment,and the observation group was given oxygen driven atomization inhalationα2b combined with Yuanhongwai Zhike Plas ter on the basis of routine comprehensive treatment.The clinical effect,disappearance time of clinical symptoms,hospital stay and lung function were compared between two groups.Results The total clinical effective rate of the observation group was higher than that of the control group,the difference was statistically significant(P<0.05).The disappearance time of wheezing,cough and lung rale,time for temperature returning to normal and hospital stay in the observation group were shorter than those in the control group,the differences were statistically significant(P<0.05).The results of tidal volume,peak time ratio and peak volume ratio in the observation group after treatment were higher than those in the control group,the differences were statistically significant(P<0.05).Conclusion Atomized inhalation of Recombinant Human Interferonα2b combined with Yuanhongwai Zhike Plaster in the treatment of bronchiolitis plays an important role in improving the treatment efficiency,shortening the disappearance time of clinical symptoms,hospitalization time and improving pulmonary function,which is worthy of popularization.

关 键 词：毛细支气管炎 雾化吸入 肺功能 重组人干扰素Α2B 远红外止咳贴 

分 类 号：R725.6[医药卫生—儿科]