藜芦中甾体生物碱的研究进展  

Research Progress of Steroidal Alkaloids in Veratrum nigrum

作　　者：王丹[1,2] 于志晶[2] 蔡勤安[2] 李虎林[1] 马瑞[2] WANG Dan;YU Zhijing;CAI Qin’an;LI Hulin;MA Rui(College of Agronomy,Yanbian University,Yanji 133002;Institute of Agricultural Biotechnology,Jilin Academy of Agricultural Sciences/Jilin Provincial Key Laboratory of Agricultural Biotechnology,Changchun 130033,China)

机构地区：[1]延边大学农学院,吉林延吉133002 [2]吉林省农业科学院生物技术研究所/吉林省农业生物技术重点实验室,长春130033

出　　处：《东北农业科学》2022年第1期151-155,共5页Journal of Northeast Agricultural Sciences

基　　金：吉林省农业科技创新工程项目(CXGC2017ZY029)。

摘　　要：甾体生物碱是藜芦植物体内的一类次生代谢物质,主要分布在藜芦的根、茎、叶中,具有抗肿瘤、降血压、镇痛消炎等多种生理功能。目前,甾体生物碱的分离纯化、药理功能、生物合成以及转录调控等研究一直是研究热点。本文主要论述藜芦甾体生物碱的药理功能、甾体生物碱合成途径的分子生物学研究,为以后藜芦甾体生物碱生物合成途径、药理作用等研究奠定基础。Steroidal alkaloids are secondary metabolites in Veratrum nigrum.They are mainly distributed in the roots,stems and leaves of V.nigrum,which have many physiological functions such as anti-tumor,lowering blood pressure and analgesic anti-inflammatory.At present,steroidal alkaloids extraction,pharmacological function,biosynthesis and transcriptional regulation have been the research focus.This paper mainly discusses the pharmacological function of steroidal alkaloids in V.nigrum and the molecular biology research of steroidal alkaloid synthesis pathway,which lays a certain foundation for the research of V.nigrum steroidal alkaloids in biosynthesis pathway and pharmacological action.

关 键 词：藜芦 甾体生物碱 药理作用 生物合成途径 

分 类 号：S567[农业科学—中草药栽培]