从痰、瘀论治动脉粥样硬化研究进展  

Research progress of differentiating and treating atherosclerosis from phlegm and blood stasis

作　　者：郭文平 黄永生[2] 靳宏光 GUO Wenping;HUANG Yongsheng;JIN Hongguang(Changchun University of Chinese Medicine,Changchun 130117,China;Affi liated Hospital of Changchun University of Chinese Medicine,Changchun 130021,China)

机构地区：[1]长春中医药大学,长春130117 [2]长春中医药大学附属医院,长春130021

出　　处：《吉林中医药》2022年第2期245-248,共4页Jilin Journal of Chinese Medicine

基　　金：2020年吉林省教育厅“十三五”科学技术项目(JJKH20200884KJ)。

摘　　要：动脉粥样硬化和心血管疾病的发生有着重要关联,心血管意外的发生也以动脉粥样硬化为基础。结合中医学辨证论治体系和整体观念思维,痰、瘀二者作为致病因素的同时,也是病理产物,其在动脉粥样硬化的发生、发展及转归过程中有着重要意义,贯穿于整个病理过程中。抗动脉粥样硬化的机制在于调整血脂水平、调节自噬、稳定粥样斑块、调整凝血/纤溶活性平衡、保护血管内皮。Atherosclerosis is closely related to the occurrence of cardiovascular diseases,and the occurrence of myocardial infarction is also caused by it.According to the system of treatment based on syndrome differentiation and the holism concept and thinking of traditional Chinese medicine,it is argued that phlegm and blood stasis are both pathogenic factors as well as pathological products,which are of great significance in the occurrence,development and outcome of atherosclerosis and run through its entire pathological process.The mechanism of anti-atherosclerosis lies in regulating the blood lipid level and autophagy,stabilizing atherosclerotic plaques,regulating the balance between coagulation and fibrinolytic activity,and protecting the vascular endothelium.

关 键 词：动脉粥样硬化 痰浊 瘀血 

分 类 号：R285[医药卫生—中药学]