感染防控体系构建对创伤性骨折患者围术期院内感染的预防价值研究  

Study on the preventive value of infection prevention and control system for perioperative nosocomial infection in patients with traumatic fracture

作　　者：周葱聪[1] 林楚君[1] 洪静[1] ZHOU Cong-cong;LIN Chu-jun;HONG Jing(Department of Orthopedics,the Second Affiliated Hospital of Wenzhou Medical University,Wenzhou,Zhejiang 325000,China)

机构地区：[1]温州医科大学附属第二医院骨科,浙江温州325000

出　　处：《中华全科医学》2022年第1期165-168,共4页Chinese Journal of General Practice

基　　金：浙江省教育厅一般科研项目(Y202044407)。

摘　　要：目的感染为创伤性骨折常见的并发症,严重者会危及生命,对创伤性骨折患者院内感染进行有效预防具有必要性,通过探讨构建感染防控体系的价值,为临床预防院内感染提供指导。方法以随机样本抽样法,在温州医科大学附属第二医院(2019年7月-2020年9月)收治的创伤性骨折患者中,收集88例,以随机数字表法分为对照组(常规干预)、观察组(构建感染防控体系),比较2组患者院内感染发生率、炎性因子指标、骨折愈合情况、并发症发生率。结果观察组院内感染发生率(2.27%)明显低于对照组(18.18%),差异有统计学意义(P<0.05)。干预前,2组患者CRP、IL-1β、TNF-α水平比较差异无统计学意义(均P>0.05);干预后,观察组CRP[(7.89±1.40)mg/L]、IL-1β[(20.08±3.11)pg/mL]、TNF-α[(7.89±1.20)pg/mL]水平均低于对照组[(11.01±1.42)mg/L、(25.11±3.34)pg/mL、(12.01±1.40)pg/mL,均P<0.05]。观察组临床愈合率(93.18%)、骨折愈合率(100.00%)均高于对照组(77.27%、81.82%,均P<0.05)。观察组并发症发生率(4.55%)低于对照组(20.45%),差异有统计学意义(P<0.05)。结论感染防控体系构建应用效果显著,可有效降低创伤性骨折术后并发症发生率,改善炎症指标与骨折愈合情况。Objective Infection is a common complication of traumatic fracture,which can be life-threatening in severe cases.It is necessary to effectively prevent nosocomial infection in patients with traumatic fracture.By discussing the value of constructing infection prevention and control system,we can provide guidance for clinical prevention of nosocomial infection.Methods Total 88 patients with traumatic fracture collected in our hospital from July 2019 to September 2020 were randomly divided into control group(routine intervention)and observation group(construction of infection prevention and control system).The nosocomial infection rate,inflammatory factor index,fracture healing and complication rate of the two groups were compared.Results The incidence of nosocomial infection in the observation group(2.27%)was significantly lower than that in the control group(18.18%),the difference was statistically significant(P<0.05).Before intervention,there was no significant difference in the level of CRP,IL-1βand TNF-αin the two groups(all P>0.05).After intervention,the levels of CRP[(7.89±1.40)mg/L],IL-1β[(20.08±3.11)pg/mL]and TNF-α[(7.89±1.20)pg/mL]in the observation group were lower than those in the control group[(11.01±1.42)mg/L,(25.11±3.34)pg/mL,(12.01±1.40)pg/mL,all P<0.05].The clinical healing rate(93.18%)and fracture healing rate(100.00%)in the observation group were higher than those in the control group(77.27%and 81.82%,all P<0.05).The incidence of complications in the observation group(4.55%)was lower than that in the control group(20.45%,P<0.05).Conclusion The construction and application of infection prevention and control system has a significant effect,which can effectively reduce the incidence of postoperative complications of traumatic fracture and improve inflammatory indexes and fracture healing.

关 键 词：院内感染 创伤性骨折 并发症 骨折愈合 

分 类 号：R683[医药卫生—骨科学] R473.6[医药卫生—外科学]