多巴胺在子痫前期及妊娠期高血压中的作用及其研究的进展  

Role of dopamine in preeclampsia and gestational hypertension and it′s research progress

作　　者：张静[1] 王宇光[1] ZHANG Jing;WANG Yu-guang(Department of Obstetrics and Gynecology,First Affiliated Hospital of Harbin Medical University,Harbin,Heilongjiang,150001,China)

机构地区：[1]哈尔滨医科大学第一附属医院妇产科,黑龙江哈尔滨150001

出　　处：《心血管康复医学杂志》2022年第1期111-114,共4页Chinese Journal of Cardiovascular Rehabilitation Medicine

摘　　要：目前妊娠期高血压疾病的发病机制尚不清楚,主要认为与子宫螺旋动脉重铸不足、炎症因子释放、血管内皮损伤等有关。研究表明,多巴胺及与其代谢相关物质在机体内的氧化应激反应对妊娠期高血压疾病的发生及发展起到重要的作用,本文将系统综述多巴胺等在子痫前期及妊娠期高血压发病机制中的作用及研究进展。At present,the pathogenesis of hypertensive disorders of pregnancy(HDP)is still unclear.It is mainly considered to be related to insufficient recasting of uterine spiral artery,the release of inflammatory factors,and vascular endothelial injury etc.Researches indicate that oxidative stress reactions of dopamine and its metabolism-related agents in vivo play an important role in occurrence and development of HDP.The present article makes a systematic review on role of dopamine etc in pathogenesis of preeclampsia and gestational hypertension and it′s research progress.

关 键 词：高血压 妊娠性 子痫 多巴胺 

分 类 号：R714.246[医药卫生—妇产科学]