血尿酸水平与老年抑郁症患者躯体化症状的关系  

Analysis of the Relationships between Serum Uric Acid Level and Somatization Symptoms in Elderly Depressive Patients

作　　者：葛晓丹 张玉龙 许雪荣 王艳玲 李群 刘季 GE Xiaodan;ZHANG Yulong;XU Xuerong(Xuzhou Oriental People’s Hospital,Xuzhou City,Jiangsu Province 221000)

机构地区：[1]江苏省徐州市东方人民医院,221000

出　　处：《医学理论与实践》2022年第4期551-553,568,共4页The Journal of Medical Theory and Practice

摘　　要：目的:探讨血尿酸水平与老年抑郁症患者躯体化症状的关系。方法:选取我院2016年3月—2019年3月收治的60例初诊老年抑郁症患者记为疾病组;另选取同时间段体检的60例健康老年人记为对照组。检测并对比两组血尿酸水平;对比疾病组不同抑郁程度尿酸水平;统计疾病组的躯体化症状,并对比不同躯体化症状患者尿酸水平差异。结果:疾病组血尿酸水平高于对照组(P<0.05);不同抑郁程度疾病组患者血尿酸水平对比差异有统计学意义(P<0.05),且重度抑郁血尿酸水平高于轻度、中度抑郁(P<0.05),中度抑郁血尿酸水平高于轻度抑郁(P<0.05);疾病组失眠、头痛、头晕、脑鸣、耳鸣、消化道不适、心悸、尿频、出汗、性症状、体质量减轻者占比分别为68.33%、53.33%、50.00%、15.00%、30.00%、58.33%、48.33%、48.33%、65.00%、28.33%、25.00%,且有上述躯体化症状者血尿酸水平均对应高于无上述躯体化症状者(P<0.05);经Spearman分析法分析,疾病组躯体化症状中有头痛、消化道不适、体重质量减轻症状的患者与血尿酸水平呈显著正相关性(P<0.05),其他症状无相关性(P>0.05)。结论:老年抑郁症患者血尿酸水平偏高,与病情程度、各项躯体化症状也有关联。Objective:To explore and analyze the relationship between serum uric acid level and somatization symptoms in elderly depressive patients.Methods:60 newly diagnosed elderly depressive patients in our hospital from March 2016 to March 2019 were selected as the disease group.60 healthy elderly people who underwent physical examination at the same time were selected as the control group.The levels of serum uric acid were detected and compared between the two groups.The levels of serum uric acid in different depressive degrees in the disease group were compared.The somatization symptoms of the disease group were counted.The difference of serum uric acid level in different somatization symptoms was compared.Results:The level of serum uric acid in the disease group was higher than that in the control group(P<0.05).The level of serum uric acid in patients with different degrees of depression was significantly different(P<0.05),and the level of serum uric acid in patients with severe depression was higher than those in patients with mild and moderate depression(P<0.05),while the level of serum uric acid in patients with moderate depression was higher than that in patients with mild depression(P<0.05).The proportion of insomnia,headache,dizziness,tinnitus,digestive tract discomfort,palpitation,frequency of urination,sweating,sexual symptoms and weight loss in the disease group were 68.33%,53.33%,50.00%,15.00%,30.00%,58.33%,48.33%,48.33%,65.00%,28.33%,25.00%,respectively.The levels of uric acid in the patients with the above somatization symptoms were corresponding.It was higher than those without the above somatization symptoms(P<0.05).According to the analysis of Spearman analysis,the patients with somatization symptoms in the disease group with headache,gastrointestinal discomfort,weight loss symptoms and serum uric acid levels were significantly positively correlated(P<0.05),and other symptoms were not correlated(P>0.05).Conclusion:The level of serum uric acid in elderly depressive patients is high,which is positively c

关 键 词：血尿酸 老年人 抑郁症 躯体化症状 

分 类 号：R589[医药卫生—内分泌] R446[医药卫生—内科学]