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作 者:庞洋 孙金钥[1] 孟丹丹 董海燕[1] 王淼 谢宁 康天虹 党艺 PANG Yang;SUN Jinyao;MENG Dandan;DONG Haiyan;WANG Miao;XIE Ning;KANG Tianhong;DANG Yi(Pharmacy Department,the First Affiliated Hospital of Xi'an Jiaotong University,Xi'an 710061;Pharmacy Department,Xianyang Hospital of Yan'an University,Xianyang 712000,China)
机构地区:[1]西安交通大学第一附属医院药学部,陕西西安710061 [2]延安大学咸阳医院药学部,陕西咸阳712000
出 处:《临床医学研究与实践》2022年第4期5-9,共5页Clinical Research and Practice
基 金:延安大学咸阳医院科研项目(No.2020ZX046)。
摘 要:目的使用Beers标准(2019版)对某院门急诊老年患者潜在不适当用药(PIM)情况进行系统分析,为促进患者用药安全提供依据。方法回顾性抽取某院2020年第四季度门急诊处方,对65岁及以上的老年患者用药情况进行统计分析,以Beers标准(2019版)为评判依据,评价老年患者PIM情况。结果共收集该院2020年第四季度门急诊老年患者处方66 884张。根据Beers标准(2019版),老年人PIM共6 330例(9.46%),排名前3的依次是中枢神经系统用药(3 755例)、胃肠道系统用药(1 057例)、内分泌系统用药(884例);老年人慎用的PIM 2 156例,药物-疾病或药物-综合症相互作用的PIM 63例。结论该院门急诊老年患者用药存在一定的PIM风险,建议重视老年患者PIM,尤其是中枢神经系统、胃肠道系统、内分泌系统药物的使用,以减少或避免PIM对老年患者的损害。Objective To systematically analyze the potential inappropriate medication(PIM) of elderly patients in outpatient and emergency department of a hospital by using Beers standard(2019 edition), so as to provide basis for promoting the drug safety of patients. Methods The prescriptions of outpatient and emergency department of a hospital in the fourth quarter of 2020 were retrospectively selected, and the medication of elderly patients with aged ≥65 years old was statistically analyzed. Based on the Beer standard(2019 edition), the PIM of elderly patients was evaluated. Results A total of 66 884 prescriptions for elderly patients in outpatient and emergency departments in the fourth quarter of 2020 were collected. According to Beers standard(2019 edition), there were 6 330(9.46%) case of PIM in the elderly, the top three were central nervous system drugs(3 755 cases), gastrointestinal system drugs(1 057 cases) and endocrine system drugs(884 cases);there were 2 156 cases of PIM used with caution in the elderly, and 63 cases of PIM with drug-disease or drug-syndrome interaction. Conclusion There is a certain PIM risk in elderly patients in outpatient and emergency department of the hospital. It is suggested to pay attention to the PIM in elderly patients, especially the use of central nervous system, gastrointestinal system and endocrine system drugs, so as to reduce or avoid the damage of PIM to elderly patients.
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