碳离子治疗技术的临床应用进展  

The Progress in Clinical Application of Carbon Ion Therapy Technology

作　　者：李京 宋英鹏 宋新宇 戴谷宇 李治斌 刘亚昕 王光宇 李光俊[1] 柏森[1] LI Jing;SONG Yingpeng;SONG Xinyu;DAI Guyu;LI Zhibin;LIU Yaxin;WANG Guangyu;LI Guangjun;BAI Sen(Department of Radiotherapy,West China Hospital,Sichuan University,Sichuan Chengdu 610041,China)

机构地区：[1]四川大学华西医院放疗科,四川成都610041

出　　处：《中国医疗设备》2022年第2期150-153,171,共5页China Medical Devices

基　　金：国家自然科学基金(81972848)。

摘　　要：放疗与手术、药物治疗等均为肿瘤的常见治疗方法,随着医用加速器设备的发展和计算机辅助技术的进步,全球多家医疗中心均在建设碳离子治疗装置。重离子在放疗方面有独特的物理和生物学优势,与常规光子治疗相比,碳离子的相对生物学效应高,能更好地保护正常组织,对乏氧癌细胞杀伤力更强。碳离子治疗的精准性高度依赖治疗计划系统、束流扩展、运动管理及图像引导等方面的技术,目前这些相关技术仍需通过大量临床验证来改进。Radiotherapy,surgery and drug treatment are common methods for cancer.With the development of the medical accelerator equipment and the computer-aided technology,carbon-ion therapy devices are being built in many medical centers around the world.Heavy ions has unique physical and biological advantages in radiotherapy.Compared with conventional photon radiotherapy,carbon-ion therapy has higher relative biological effectiveness which can protect normal tissue better and is more lethal to hypoxic cancer cells.The accuracy of carbon-ion therapy is highly dependent on radiotherapy technologies such as treatment planning system,beam delivery,motion management and image guidance,which still need to be improved through a large number of clinical verification at present.

关 键 词：碳离子治疗 束流扩展 运动管理 治疗计划系统 图像引导 

分 类 号：R445.1[医药卫生—影像医学与核医学] R739.91[医药卫生—诊断学]