磁共振波谱联合弥散加权成像诊断前列腺癌的价值研究  

Study on the value of MRS combined with DWI in diagnosing PCa

作　　者：尹树国 张涛 赵东 YIN Shu-guo;ZHANG Tao;ZHAO Dong(Department of Radiology,People's Hospital of Dongying District of Dongying City,Dongying 257000,China;不详)

机构地区：[1]东营市东营区人民医院放射科,山东东营257000

出　　处：《中国医学装备》2022年第2期46-49,共4页China Medical Equipment

摘　　要：目的:探讨磁共振波谱(MRS)联合MR弥散加权成像(DWI)对前列腺癌(PCa)的诊断价值。方法:选取医院收治的24例PCa患者纳入PCa组;另选取32例良性前列腺肥大(BPH)患者纳入BPH组;同期选取在医院进行颅脑检查的30名健康志愿者纳入健康对照组。3组受检者均行MRS及DWI磁共振检查,并测定各组受检者诊断阳性率、灵敏度、特异度和准确率。采用受试者工作特征(ROC)曲线下面积(AUC)统计分析MRS检查、DWI检查及MRS联合DWI检查方法在PCa中的诊断效能。结果:PCa组、BPH组和健康对照组的MRS、DWI诊断阳性率差异有统计学意义(F=11.281,F=10.315;P<0.05);PCa组MRS、DWI诊断阳性率明显高于BPH组及健康对照组,差异有统计学意义(χ^(2)_(MRS)=8.315,χ^(2)=9.327;χ^(2)_(DWI)=11.259,χ^(2)=10.316;P<0.05);联合诊断PCa准确率显著高于单纯MRS、DWI诊断,差异有统计学意义(χ^(2)=9.358,P<0.05);MRS、DWI和MRS联合DWI检测PCa的AUC分别为0.716、0.785和0.918,MRS联合DWI诊断的AUC显著高于单纯MRS、DWI检查,差异有统计学意义(χ^(2)=12.257,χ^(2)=18.351;P<0.05)。结论:MRS联合DWI检测能有效提高PCa诊断的特异性及敏感性,具有临床诊断价值。Objective:To explore the diagnostic value of magnetic resonance spectroscopy(MRS)combined with MR diffusion weighted imaging(DWI)on prostate cancer(PCa).Methods:24 patients with PCa who admitted to hospital were selected and included in PCA group,and 32 patients with benign prostatic hypertrophy(BPH)were included in BPH group.In the same period,30 healthy volunteers who underwent brain examination in hospital were included in healthy control group.All patients of three groups underwent MRS and MR DWI examination,and the diagnostic positive rate,sensitivity,specificity and accuracy of them in each group were measured.The area under curve(AUC)of receiver operating characteristic(ROC)curve was adopted to statistically analyze the diagnostic efficacies of MRS examination,DWI examination and the combined examination on PCa.Results:There were significant differences in the diagnostic positive rates of MRS and DWI among PCa group,BPH group and healthy control group(F=11.281,F=10.315,P<0.05),respectively.The diagnostic positive rates of MRS and DWI in PCa group were significantly higher than those in BPH group and healthy control group(χ^(2)_(MRS)=8.315,χ^(2)=9.327,χ^(2)_(DWI)=11.259,χ^(2)=10.316,P<0.05),respectively.The accuracy of combined diagnosis was significantly higher than that of MRS and DWI diagnosis for PCa(χ^(2)=9.358,P<0.05).The AUCs of MRS,DWI and the combined examination were 0.716,0.785 and 0.918 in diagnosing PCa,respectively.And the AUC of the combined examination of MRS and DWI was significantly higher than that of single MRS and single DWI(χ^(2)=12.257,χ^(2)=18.351,P<0.05),respectively.Conclusion:The combined examination of MRS and DWI can effectively improve the specificity and sensitivity of diagnosing PCa,and it has clinically diagnostic value.

关 键 词：MR波谱分析 弥散加权成像(DWI) 前列腺癌(PCa) 前列腺增生 联合诊断 

分 类 号：R445.2[医药卫生—影像医学与核医学]