脊柱微创通道镜下改良经椎间孔入路椎间植骨融合术治疗腰椎退行性疾病106例  

Clinical Report of 106 Cases about Lumbar Degenerative Disease Treated by Modified TLIF Operation under Minimally Invasive Spine Tunnel

作　　者：姚楚亮[1] 陈杰[1] 杜杰明 杨焱鑫[1] 曾辉[1] 王华仁[1] 廖臻[1] YAO Chuliang;CHEN Jie;DU Jieming;YANG Yanxin;ZENG Hui;WANG Huaren;LIAO Zhen(Department of Spinal Surgery,Guangdong Provincial Armed Police Corps Hospital,Guangzhou 510000,China)

机构地区：[1]武警广东省总队医院脊柱外科,广州510000

出　　处：《中国中医骨伤科杂志》2022年第1期74-77,共4页Chinese Journal of Traditional Medical Traumatology & Orthopedics

基　　金：广东省医学科学技术研究基金项目(A2018416)。

摘　　要：目的:讨论脊柱微创通道镜下改良TLIF术治疗腰椎退行性疾病的疗效。方法:回顾性收集2018年6月至2020年6月收治的106例腰椎退行性疾病患者,采用改良微创TLIF术联合单侧钉棒固定,分析患者的JOA评分、手术时间、术中出血量等围手术期指标。同时,比较术前、术后12 h、术后24 h氧化应激指标、疼痛评分、功能障碍评分指标情况。结果:围手术期指标情况:手术时间为(101.38±4.45)min,术中出血量为(355.08±21.85)mL,JOA评分为(93.77±2.13)分,围手术期指标较好。氧化应激指标、疼痛评分、功能障碍评分指标情况:与术前相比,术后12 h及术后24 h在椎间隙高度、血糖、皮质醇、疼痛评分、Oswestry功能障碍评分上都要优于术前情况,差异有统计学意义(P<0.05)。与术后12 h相比,术后24 h的血糖、皮质醇、疼痛评分、Oswestry功能障碍评分上都要优于术后12 h情况,差异有统计学意义。结论:改良微创TLIF术治疗退行性腰椎疾病有效,可减少氧化应激反应,提升患者腰椎功能。Objective:To observe the clinical efficacy of modified TLIF operation under minimally invasive spine tunnel.Methods:A retrospective study was conducted for 106 lumbar degenerative diseases patients underwent modified minimally invasive TLIF surgery from June 2018 to June 2020.Patients’ JOA score,operation time and blood loss were analyzed.The oxidative stress index,pain score,and dysfunction score before operation,12 and 24 h after operation were compared.Results:Operation time was(101.38±4.45) min.Intraoperative blood loss was(355.08±21.85) mL.JOA score was(93.77±2.13) point.Perioperative indicators have certain application value.Pain,dysfunction score,characteristic index score were as follow:intervertebral space height,blood glucose,cortisol pain score and Oswestry dysfunction at the 12 h and 24 h after treatment were improved as compared with these before the treatment(P<0.05).Blood glucose,cortisol pain score and Oswestry dysfunction at the 24 h after treatment were improved as compared with these at 12 h after treatment(P<0.05).Conclusion:The modified minimally invasive TLIF operation is effective in the treatment of degenerative lumbar spine diseases,which can reduce oxidative stress,improve the patient’s lumbar spine function,and promote the patient’s recovery.

关 键 词：改良经椎间孔入路椎间植骨融合术 腰椎退行性疾病 氧化应激 腰椎功能 

分 类 号：R681.5[医药卫生—骨科学]